Relationship Between Muscle Strength and Physical Function in ICU

Analysis of the Relationship Between Muscle Strength and Physical Function in ICU Survivors

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT04284475

Enrollment

Registered

2020-02-25

Start date

2018-10-01

Completion date

2021-11-01

Last updated

2021-11-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Critical Illness, Muscle Weakness, Physical Disability, Physical Dependence

Brief summary

This observational study aims to assess the relationship between muscle strength and physical function in critical ill patients. Grip and quadriceps strengths are measured using a standardized protocol of dynamometry. Physical function is assessed using the validated ICU mobility scale.

Interventions

DIAGNOSTIC_TESTQuadriceps strength

Using a handheld dynamometer, in supine position in a standardized position of the dominant leg Measurement of the maximal isometric voluntary quadriceps contraction Measure expressed as Newton and Newton/kg

DIAGNOSTIC_TESTGrip strength

Testing of dominant hand using a handgrip Measurement of the maximal isometric voluntary grip contraction Measure is expressed as kg

DIAGNOSTIC_TESTICU mobility scale

Scoring the physical capacity of the patient on a 10-points validated scale: the ICU mobility scale

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* ICU stay of at least 48h * Collaborative (RASS score -1 to +1)

Exclusion criteria

* Refusal * Coma * Non collaborative * Hemi / tetra paresis or plegia

Design outcomes

Primary

Measure	Time frame	Description
Quadriceps strength	as soon as collaborative during ICU stay and up to 1 month following ICU discharge	Quadriceps maximal isometric strength measured using dynamometry
Handgrip strength	as soon as collaborative during ICU stay and up to 1 month following ICU discharge	Grip maximal isometric strength measured using dynamometry
ICU mobility scale	as soon as collaborative during ICU stay and up to 1 month following ICU discharge	Ranking the patient on the scale according to his/her physical capacity. ICU mobility scale is a 10 points scale: 0 means the patient is lying in bed, 10 means the patient is able to walk independently

Countries

Belgium

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026