Insomnia
Conditions
Keywords
Insomnia, Cognitive training, Sleep, Cognition, Polysomnography, Actigraphy, Older Adults
Brief summary
The purpose of this research is to look at the effects of computerized cognitive training on sleep, mental abilities (cognition), and other aspects of daytime functioning, such as mood, and arousal
Interventions
BEHAVIORALCognitive Training
Participants (n=20) provided game console with cognitive training games and activities.
BEHAVIORALWLC (Waitlist Control)
Participants (n=20) will receive the cognitive training intervention later, following week 8 assessments.
Sponsors
American Academy of Sleep Medicine
University of Missouri-Columbia
Study design
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
TREATMENT
Masking
SINGLE (Outcomes Assessor)
Intervention model description
Participants will be randomly assigned to either the cognitive training or waitlist control(WLC). In both conditions, they will receive the intervention, but the waitlist control will receive this later. Both groups will complete 6 weeks of the cognitive training game either immediately after 1 week baseline (cognitive training group) or after the week 8 assessments (WLC).
Eligibility
Sex/Gender
ALL
Age
60 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
* 60+ yrs of age. * No neurological or psychiatric illness, dementia, or loss of consciousness \> 5 mins. * Nongamers (i.e. \<1 hour of video/cognitive training games per week over last 2 years) * Proficient in English (reading and writing). * Meet clinical diagnosis for Insomnia. Insomnia: * Insomnia complaints for 6+ months. * Complaints occur despite adequate opportunity and circumstances for sleep. * Consist of 1+ of the following: difficulty falling asleep, staying asleep, or waking up too early * Daytime dysfunction (mood, cognitive, social, occupational) due to insomnia.
Exclusion criteria
. * Unable to provide informed consent. * Unable to undergo randomization. * Cognitive impairments (i.e. mild cognitive impairment, dementia) * Other sleep disorder (i.e., sleep apnea, Periodic Limb Movement Disorder) * Severe untreated psychiatric comorbidity that renders randomization unethical * Using psychotropic or other medications (e.g., beta-blockers) that alter sleep * Uncorrected visual/auditory impairments * Participation in nonpharmacological treatment for sleep/fatigue/mood outside the current study.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Subjective Cognitive Self-Efficacy- Cognitive Failures Questionnaire | Up to 15 weeks | A 25-item scale measuring subjective cognition. Participants rate on a scale of 0 (never) to 4 (very often) how often they experience cognitive mistakes and errors in daily tasks. |
| Objective Cognition- NIH Toolbox Cognitive Battery | Up to 15 weeks | 20-min computerized battery completed in single sitting on iPad.Domains tested include processing speed and attention, visuospatial ability and memory, verbal learning and memory, and executive functioning and working memory. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Physiological Arousal- Heart Rate Variability | Up to 15 weeks | Holter monitor assessed 5 min ECG recordings both at rest and during sleep (with PSG).Time index variables: SDNN (standard deviation of normal to normal heartbeat intervals). Spectral index variables: High frequency (0.15-0.4 Hz), low frequency (0.04-0.15 Hz), very low frequency (below 0.04 Hz). |
| Subjective Arousal-Global Cognitive Arousal-Perceived Stress Scale | Up to 15 weeks | Perceived Stress Scale is a self-report measure of how life situations are perceived as stressful. The scale consists of 15 items corresponding to everyday situation and participants are asked to rate on a likert scale from 0 (never) to 4 (very often) how often they felt or thought a specific way. Higher scores correspond to higher perceived stress. |
| Mood- Beck Depression Inventory (II) | Up to 15 weeks | 21-item inventory that asks respondents to rate on a scale of 0 (no depressive feelings) to 3 (most depressive feelings) their feelings towards various aspects of daily living/situations. Higher total scores indicate worse depressive symptoms. |
| Alcohol Use- Alcohol Use Disorder Test | Baseline | 10-item questionnaire that assess the frequency of alcohol use and problems associated with alcohol use over the past year. |
| Mood- State-Trait Anxiety Inventory | Up to 15 weeks | Inventory that asks respondents to rate how true 20 self-descriptive statements (e.g., I feel calm) are on a 4-point scale (1 = not at all, 4 = very much so). Typically, respondents are asked to rate statements according to how they generally feel (trait-anxiety scale) and how they feel in the current moment (state-anxiety scale). Total scores range from 20 to 80, with higher scores indicating greater maladjustment. |
| Objective Behavioral Sleep - Actigraphy | Up to 15 weeks | Actiwatch 2 (Philips Respironics) is a watch-like device that monitors light and motor activity. Device is worn 24 hours a day for 7 days at each assessment, and during 6 weeks of intervention. Data analyzed by proprietary software using 30s epochs. Validated algorithm will be used to obtain sleep onset latency, wake time after sleep onset. |
| Subjective Arousal- Arousal Predisposition Scale | Up to 15 weeks | Arousal Predisposition Scale is a 12-item inventory that has been designed to measure the degree to which an individual experiences arousal. Higher scores indicate greater predisposition to arousal. |
| Subjective Behavioral Sleep- Electronic Daily Sleep Diaries | Up to 15 weeks | Electronic Daily Sleep Diaries. Online diaries completed each morning (\ 5 mins) during 1 wk assessment period and 6 weeks of intervention. Diaries measure sleep onset latency, wake time after sleep onset, total sleep time, and sleep quality. |
| Subjective Behavioral Sleep- Insomnia Severity Index | Up to 15 weeks. | Brief self-report measure of current perception of insomnia symptom severity, distress and daytime impairment. Commonly used in insomnia treatment outcome research. |
| Objective Sleep-PSG | Up to 15 weeks | Single night PSG measured sleep stages. |
| Game-related experience | Up to 6 weeks | During the intervention phase for each group, participants will complete gaming diary measuring session duration, games played. |
| Subjective Arousal- Pre-sleep Arousal Scale | Up to 15 weeks | Pre-sleep Arousal Scale is a 16-item self-report questionnaire comprising both cognitive and somatic manifestations of arousal. |
| Circadian Rhythm - Morningness-Eveningness Questionnaire | Up to 15 weeks | 19-item questionnaire that assesses preference for morning, afternoon, and evening activities. Total score reflects degree of morningness or eveningness type. |
Countries
United States
Outcome results
None listed