Albinism, Low Vision, Retinitis Pigmentosa, Stargardt Disease 1, Stargardt Disease 3, Stargardt Disease 4
Conditions
Keywords
Virtual Reality, Quality of life
Brief summary
Purpose: To validate a newly developed battery of performance-based tests of visual function to be presented using virtual reality. The tests are intended as potential outcome measures for clinical trials of treatments of eye disease: they measure visual performance in patients with low vision on visual tasks that a relevant for daily life.
Detailed description
Aims of the Research Project: 1. To validate a new virtual reality (VR)-based battery of performance-based tests of visual function that are relevant for patients' daily lives. 2. To quantify the reproducibility of the performance-based tests. 3. To gather acceptability and ease-of-use data from patients.
Interventions
DEVICEVirtual Reality Headset based tests
Visual task tests based on Oculus Rift
Sponsors
University of Sussex
Queen's University, Belfast
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
20 Years to 50 Years
Inclusion criteria
1. Male and female participants 2. Age 20-50 3. Bilateral sight impairment due to Stargardt's disease, retinitis pigmentosa or albinism. 4. Sight impairment criteria are as follows: * Visual acuity of 3 / 60 to 6 / 60 with a full field of vision. * Visual acuity of up to 6 / 24 with a moderate reduction of field of vision
Exclusion criteria
1. Any physical impairment that would make use of the virtual reality headset difficult or unsafe. 2. A history of vertigo or dizziness.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Test repeatability | All statistical analysis will take place once all data collection has ended, average 1 year. | Bland and Altman analysis will be used to investigate the repeatability of the tests between visit 1 and visit 2. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Ease of use and acceptability questionnaire | Responses from all participants will be collated and summarised at the end of the study, average 1 year. | Modified from Tay et al, Br J Ophthalmol 2004;88:719-720 Ask the following questions for virtual reality test: 1. Was the test comfortable? If no- How? 2. Was the test too long? 3. How did you find the test? Would you describe it as easy or difficult? If you found it difficult- how? 4. How would you feel if you knew you had to perform this test at every clinic appointment? 5. Do you have any other comments about the test? |
Countries
United Kingdom
Contacts
Primary ContactRuth Hogg, PhD
Backup ContactLucie Dalton, BSc
Outcome results
None listed