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Medium-chain Triglyceride Oil Massage on Growth in Preterm

The Effect of Medium-chain Triglyceride Oil Massage on Physical Growth in Preterm Infants Weighing Between 1500 and 2000 g: a Prospective Randomized Trial

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT04281563
Enrollment
48
Registered
2020-02-24
Start date
2017-07-07
Completion date
2019-07-06
Last updated
2020-02-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Growth, MCT Oil Massage, Preterm Infants

Brief summary

Aim: To explore the effect of medium-chain triglyceride (MCT) oil massage on growth in preterm infants. Methods: This randomized controlled trial was conducted in the newborn center of a regional hospital in Taiwan. Preterm infants weighing between 1500 and 2000 g were recruited and randomly assigned to three groups: the MCT oil massage, massage alone and no massage groups. The massages were given three times per day for 7 consecutive days. Weight, length and head circumference were measured in the three groups at birth and on study days 1 to 7.

Interventions

OTHERmassage with MCT oil (group 1)

Two trained nurse took turns performing standardized massage techniques in group 1 and group 2. The difference was that in group 1, the neonates received massage with MCT oil, and in group 2, the neonates received massage without using the oil. The 10-min massage intervention consisted of two 5-min phases: tactile and kinesthetic stimulation (13), which were given three times a day for 7 consecutive days. The massage force was approximately 300 grams, and the massager practiced applying the pressure by using a food scale. The massage was given in the prone and supine positions, and the actions included gentle touching of the head, back and limbs for five 1-min periods, followed by six passive flexion/extension movements lasting 10 s apiece for each arm, then each leg, and finally both legs together for a total of five 1-min periods. Premature infants in the oil massage group received massage with 10 mL/kg/day of MCT oil divided equally into three applications.

Sponsors

Chiayi Christian Hospital
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
HEALTH_SERVICES_RESEARCH
Masking
SINGLE (Investigator)

Masking description

Data were analyzed by a researcher who was not informed of the intervention group assignment.

Eligibility

Sex/Gender
ALL
Age
28 Weeks to 37 Weeks
Healthy volunteers
No

Inclusion criteria

1. gestational age between 28 and 37 weeks; 2. weight between 1500 and 2000 g after enrollment; 3. medically stable condition; 4. ≥120 cc per day feeding.

Exclusion criteria

1. congenital anomalies; 2. skin disease; 3. requirement for mechanical ventilation; 4. requirement for O2 therapy; 5. presence of fracture.

Design outcomes

Primary

MeasureTime frameDescription
weighton study days 1 to 7weight increase

Secondary

MeasureTime frameDescription
height and head circumferenceon study days 1 to 7height and head circumference increase

Countries

Taiwan

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 14, 2026