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A Longitudinal, Observational Biomarker Study in Pancreatic Cancer Patients Receiving Chemotherapy

A Longitudinal, Observational Biomarker Study in Pancreatic Cancer Patients Receiving Chemotherapy

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT04281511
Enrollment
238
Registered
2020-02-24
Start date
2019-04-03
Completion date
2023-09-30
Last updated
2023-11-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pancreatic Cancer

Keywords

Pancreatic cancer, Biomarker, chemotherapy, pharmacogenomic, clinical trials

Brief summary

1. Based on the literature, the pancreatic cancer treatment predictor biomarker, which is used in the domestic clinical field, is actually applied to the pancreatic cancer patient cohort of the National Cancer Center. 2. To systematically prospectively identify prospective treatment response biomarkers for Pancreatic Cancer Cohort in the National Cancer Center

Detailed description

1. Immunohistochemistry and gene test for hENT1, DCK, SMAD4, CES2, BRCA 1/2,PALB2, MMRd, MSI, Tumor Ag and etc. on Cancer sample 2. Collect data of Biomarker for pancreatic cancer 3. Compare with Big data and Cohort study in National cancer center 4. The number of subjects is changed by statistical consideration. 218-\>238

Interventions

None listed

Sponsors

National Cancer Center, Korea
Lead SponsorOTHER_GOV

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Healthy volunteers
No

Inclusion criteria

* Pathologically Confirmed Pancreatic Cancer Patients

Exclusion criteria

* Subjects who do not agree with the study

Design outcomes

Primary

MeasureTime frameDescription
median survival5 yearsThe length of time from either the date of diagnosis or the start of treatment for a disease,the length of time during and after the treatment of a disease, such as cancer, that a patient lives with the disease but it does not get worse
progressive-free survival5 yearsThe length of time during and after the treatment of a disease, such as cancer, that a patient lives with the disease but it does not get worse

Countries

South Korea

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026