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Impact of Tooth Loss and Denture on Oral Senses and Food Preferences

Impact of Complete Tooth Loss and Denture on Oral Sensory Abilities and Food Preference

Status
Recruiting
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT04281056
Acronym
AlimaPAC
Enrollment
40
Registered
2020-02-21
Start date
2022-03-16
Completion date
2027-04-30
Last updated
2025-12-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Tooth-loss

Keywords

Teeth loss, edentulousness, denture, tast, trigeminal senses, oral sensory ability

Brief summary

Tooth loss impacts taste abilities and food intake. Present study aims at pertaining the impact of teeth loss and the replacement by means of complete denture on taste and trigeminal abilities, and on food preferences, and taste appetence.

Detailed description

Two groups of participants will be included. Participants wearing complete denture for at least one year (n=20) and their matched controls for age, sex, tobacco, and saliva secretion (n=20). Their oral sensory abilities of participants will be assessed including taste (electrogustometric thresholds, chemical taste identification ability) and trigeminal quantitative sensory testing. Food preferences and selectivity (Maitre et al., 2014) and taste appetence (Deglaire et al., 2012) will also be assessed.

Interventions

PROCEDURETooth removal and their replacement by means of a denture

Teeth have been removed and replaced by means of dentures for at least one year

Sponsors

Assistance Publique - Hôpitaux de Paris
Lead SponsorOTHER

Study design

Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
BASIC_SCIENCE
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
18 Years to 79 Years
Healthy volunteers
No

Inclusion criteria

Study Group : being completely edentulous and wearing denture for at least one year, wearing denture during meals, with clean and stable dentures. Controls: controls Group : dentate subjects (25 teeth at leas, non endodontically treated) with molars in Angle's Class I occlusion, having no functional disturbance of mastication and not undergoing dental treatment at the time of the recording. Matched with subjects of the study group for age, sex, tabacco consumption, and saliva flow rate.

Exclusion criteria

* Aged under 18 or over 80 Y, * not consenting to participate * suffering from dental * periodontal or gum pain for the last month.

Design outcomes

Primary

MeasureTime frameDescription
taste detection thresholdsup to 30 daysUsing an Electrogustometer

Secondary

MeasureTime frameDescription
Chemical taste identification abilityup to 30 daysUsing taste strips (Burghard)
Quantitative sensory testingup to 30 daysUsing an algometer, von frey filament, a thermode.
Food preferences and selectivityup to 30 daysQuestionnaire food selectyivity and preference (Maitre et al., 2014)
Taste appetenceup to 30 daysQuestionnaire PrefQuest (Deglaire et al., 2012)

Countries

France

Contacts

Primary ContactAdeline Braud, Doctor
adeline.braud@aphp.fr01 40 19 39 87
Backup ContactYves Boucher, Professor

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026