Skip to content

23-gauge Pars Plana Vitrectomy With Silicone Oil Injectionsilicone Oil Injection With Surgical

Surgical Techniques for Epiretinal Membrane Removal in Pars Plana Vitrectomy: A Comparative Study Between 20-Gauge and 23-Gauge Vitrectomy

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT04280770
Enrollment
50
Registered
2020-02-21
Start date
2009-01-30
Completion date
2013-03-30
Last updated
2020-02-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Retinal Detachment

Keywords

retina, silicone, laser, break, vitrectomy

Brief summary

Objective: to evaluate anatomical and visual outcomes of 23-gauge vitrectomy for retinal detachment with silicone oil injection in fifty cases. The rate of recurrence, the incidence of proliferative vitreoretinopathy (PVR) and the value of risk factors. Participants and Methods: fifty cases with RD with mixture of epiretinal and subretinal membranes were collected. Pars plan vitrectomy, 23gauge vitrectomy were done to these cases, then silicone oil removed 6 weeks after primary surgery. Main Outcome Measures: The anatomical success rate,the failure rate ,the rate of retinal breaks in both groups, and reproliferation rate.

Detailed description

50 Patients were included if they had retinal detachment, moderate degrees of PVR, PVR ≥ Grade C, previous buckle surgery and pseudophakia. A good and correct assessment of the detached retina was done. Investigator followed the Lincoff rules to find the retinal breaks. Investigator performed a three-port vitrectomy: one infusion trocar and two instruments trocars. Non-contact wide-angle viewing systems (Resight- Biom) have a viewing field of 60-130° was used. Investigator used Perfluorocarbon liquid (PFCL) for attaching the retina with its gravity. Then performing PFCL against air exchange.The retina will be attached under air tamponade. Laser photocoagulation was performed in the air-filled eye. Investigator applied the laser effects confluently surrounding all retinal breaks. Then silicone oil (1000 centistokes) was injected as a final step and permanent tamponade.After 3-6 months investigator removed the silicone and examined the retina for 6 weeks after surgery to detect the recurrent cases.

Interventions

PROCEDURE23 PARS PLANA VITRECTOMY

We performed a three-port vitrectomy: one infusion trocar and two instruments trocars. Non-contact wide-angle viewing systems (Resight- Biom) have a viewing field of 60-130° was used. Put 23 needle attached to the automated pump for silicone oil extraction. Strict examination of the retina to detect new breaks or untreated breaks. Closure of the sclerotomies.

Sponsors

Ain Shams University
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
TRIPLE (Subject, Caregiver, Outcomes Assessor)

Masking description

Each of the recruited patients were assigned a study number and randomized in accordance with a simple block randomization scheme.

Intervention model description

Fifty participants were assigned and divided into two groups. Participants without RD after SO removal was recruited into group A-NRD, and participants with RD after SO removal was recruited into group B-RD.

Eligibility

Sex/Gender
ALL
Age
23 Years to 58 Years
Healthy volunteers
No

Inclusion criteria

* they had retinal detachment, * moderate degrees of PVR * PVR ≥ Grade C * previous buckle surgery * pseudophakia.

Exclusion criteria

* the retinal tear was greater than 90 degrees * presence of intravitreal foreign body * previous vitrectomy done before * if follow-up data were unavailable for a minimum follow-up of 6 months following the final retinal procedure.

Design outcomes

Primary

MeasureTime frameDescription
success rate42 dayssuccess rate after first RD surgery and silicone oil removal
The failure rate42 daysThe failure rate after silicone oil removal
number of surgical interference4 yearsnumbers of vitrectomies done after silicone oil removal

Secondary

MeasureTime frameDescription
lower retinal breaks4 yearsThe rate of lower retinal breaks in RD group versus the rate of lower retinal breaks in NRD group was

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026