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Engaging Practices and Communities in the Development of Interventions to Promote HPV Vaccine Uptake

Engaging Practices and Communities in the Development of Interventions to Promote HPV Vaccine Uptake

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT04279964
Enrollment
2400
Registered
2020-02-21
Start date
2020-05-08
Completion date
2024-08-31
Last updated
2025-04-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Primary Prevention

Keywords

Immunization, Boot Camp Translation, Adolescent, Human Papillomavirus, Vaccine

Brief summary

The overarching goal of this project is to implement Boot Camp Translation (BCT) methodology to translate the guidelines and evidence for human papillomavirus (HPV) vaccine into a practice and provider level intervention designed to improve its acceptability and uptake.

Detailed description

As a community engagement approach, Boot Camp Translation (BCT), is a 6-9-month iterative process that brings together multiple stakeholders, including patients, parents, and community members, to translate evidence-based guidelines and recommendations into locally relevant and meaningful messages, materials, and programs. Aim 1: Implement BCT in three geographically distinct Colorado communities to translate the current evidence for HPV vaccination into locally relevant interventions designed to increase vaccine uptake. Aim 2: Evaluate the impact of the BCT- designed intervention on practice-level HPV vaccination initiation rates. The long-term goal is to develop a replicable approach and low-cost method of increasing HPV vaccine uptake that is easily adaptable to different settings and sociodemographic contexts.

Interventions

Practices in the intervention arm will participate in the Boot Camp Translation process, where BCT Community Advisory group members will come together to develop and implement practice relevant materials to promote adolescent vaccination.

OTHERControl

No intervention. Practices will continue to behave as usual.

Sponsors

National Institutes of Health (NIH)
CollaboratorNIH
National Cancer Institute (NCI)
CollaboratorNIH
University of Colorado, Denver
Lead SponsorOTHER

Study design

Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
SINGLE (Outcomes Assessor)

Eligibility

Sex/Gender
ALL
Age
9 Years to 26 Years
Healthy volunteers
No

Inclusion criteria

All child patients who have received health supervision at participating practices during the 12 month prior to intervention and the 12 month following intervention implementation, who are ages 9-26 years, and whose parents have not requested removal from the Colorado Immunization Information System (CIIS) will be eligible for the assessment of practice immunization rates in the pre and post periods.

Exclusion criteria

* No subjects will be excluded because of gender, ethnicity, or insurance status. * Any child whose parents have requested removal from the immunization registry; any child with hypersensitivity to any component of one of the recommended vaccines; any child who has moved to a primary care provider other than one at the study clinics.

Design outcomes

Primary

MeasureTime frameDescription
Initiation of HPV vaccination series, 9-17Up to 12 monthsPercent of 9-17 year olds who have received \>=1 dose of the HPV vaccine by September 29, 2021

Secondary

MeasureTime frameDescription
Differences in initiation rates between intervention vs. control, 13-1712 monthsComparison of boys vs. girls who have received \>1=dose of HPV vaccine by September 29, 2021
Differences in initiation rates between intervention vs. control, 18-2612 monthsPercent of 18-26 year olds who have received \>=1 dose of the HPV vaccine by September 29, 2021
Differences in initiation rates between intervention vs. control, 9-1012 monthsComparison of boys vs. girls who have received \>1=dose of HPV vaccine by September 29, 2021
Differences in initiation rates between intervention vs. control, 11-1212 monthsComparison of boys vs. girls who have received \>1=dose of HPV vaccine by September 29, 2021

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 17, 2026