Skip to content

Continuous Sciatic Block Nerve in the Management of Vascular Pain in Critical Ischemia of Lower Limbs Patients

Evaluation of Ultrasound Guided Continuous Sciatic Block Nerve With a Longitudinal Approach in the Management of Vascular Pain in Critical Ischemia of Lower Limbs Patients : Prospective Descriptive Study of Exploratory Cohort

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT04278014
Enrollment
13
Registered
2020-02-20
Start date
2020-06-01
Completion date
2021-02-01
Last updated
2021-05-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Critical Limb Ischemia

Brief summary

Critical limb ischemia (CLI) is associated with severe pain that is a therapeutic challenge whit therapeutic limits for the use of conventional analgesics medications. ultrasound-guided continuous sciatic block (CCBN) is strategy effective and safe to consider in this patients. This prospective descriptive exploratory cohort study evaluates CCBN as a effective therapeutic tools for patients whit (CLI)

Detailed description

Critical limb ischemia is the final stage of peripheral vascular disease identified by resting pain greater than 2 weeks with ulcers or gangrene in 1 or both extremities. Pain relief is a therapeutic challenge due to its severity, which significantly affects the quality of life, and the comorbidities that occur frequently in these patients, which limits the use of analgesics medications. Regional techniques can play an important role as they are safe and effective in analgesic management . Within these we find the ultrasound guided continuous sciatic block as a strategy to consider in the periods of exacerbation of pain, as a bridge to a palliative or resolutive management. Prospective descriptive exploratory cohort study. Patients with a diagnosis of critical ischemia of the lower limb with severe pain and side effects of opioids will be included. A continuous ultrasound-guided sciatic nerve block with longitudinal approach will be performed, with no anti-aggregation or anticoagulation suspension, continuing with an infusion of Bupivacaine 0.1% The primary outcome will be numerical pain rating scale (NPrs) and secondary outcome Pinprick test, catheter duration, opioid consumption reduction and side effects to it.

Interventions

PROCEDUREultrasound-guided continuous sciatic block with longitudinal approach

ultrasound-guided continuous sciatic block with longitudinal approach

Sponsors

Universidad de Antioquia
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Patients with a diagnosis of critical ischemia of the lower limb with severe pain and side effects of opioids

Exclusion criteria

* Under 18 years old

Design outcomes

Primary

MeasureTime frameDescription
Pain level measurement with Numeric Rate Score (NRS)5 days0-10 where 0 means no pain and 10 means maximum possible pain

Secondary

MeasureTime frameDescription
Pinprick test5 daysevaluation of superficial sensitivity in S1 dermatome positive or negative
catheter duration5 daysnumber of days in which the catheter is functional
opioid consumption reduction5 daysopioid consumption in morphine equivalence
Delirium5 daysminimental test score from 0 to 30 points. Delirium positive for less than 24
Nauseas and Vomit5 daysyes or not present

Countries

Colombia

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026