Postoperative Respiratory Complications
Conditions
Keywords
abdominal surgery, hypoxia, lung function, ventilation, Carbon dioxide partial pressure, oxygen situation, Postoperative, Positive expiratory pressure therapy
Brief summary
Hypoxia and reduced vital capacity is commonly occurring after abdominal surgery. Positive expiratory pressure is one treatment suggested to improve lung function after surgery. We aim to test whether speaking improves postoperative oxygen saturation and ventilation after abdominal surgery. In a cross-over design, 50 subjects will be randomized to start with either positive expiratory pressure maneuvers, i.e. deep inspiration followed by expiration in a positive expiratory pressure device at 10-15 cm of water, or to start with reading a text loudly. Arterial blood gases will be taken at study start. Patients will be monitored using Noxturnal T3, Res Med for respiration and pulse oximetry, and online transcutaneous carbon dioxide partial pressure measurements (SenTec Digital monitoring systems). Main outcome measurements include oxygen saturation after speaking compared with positive expiratory pressure therapy.
Detailed description
Hypoxia and reduced vital capacity is commonly occurring after abdominal surgery. Positive expiratory pressure is one treatment suggested to improve lung function after surgery, but there is a lack of evidence of effect. En passant, we observed that oxygen saturation was improved when patients talked postoperative day 1. We aim to test whether speaking improves postoperative oxygen saturation and ventilation after abdominal surgery. It was estimated that a sample size of 34 patients was needed to detect a mean and (SD) difference in oxygen saturation of 1% (2%) and to detect a difference in transcutaneous carbon dioxide partial pressure of 0.5 kPa (1 kPa) with a significance level of 0.05 and a power of 0.8. In a randomized controlled trial, 50 subjects will be randomized (1:1) to start with either positive expiratory pressure maneuvers, i.e. 3 x 10 deep inspiration followed by expiration in a positive expiratory pressure device of 10-15 cm H20 or to start with reading a text loudly during 3 minutes. Patients will be monitored using Noxturnal T3, Res Med for respiration and pulse oximetry. SenTec Digital Monitoring systems for online transcutaneous carbon dioxide partial pressure measurements.
Interventions
Three blocks of 10 deep inspiration followed by expiration against a positive airway pressure device of 10-15 cm of water pressure. Repeated three times. Estimated time of 3 minutes time.
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Sponsors
Study design
Masking description
Patients are given a serial number. The randomization orders are blinded to the outcome assessor.
Intervention model description
Positive expiratory pressure is given to patients after abdominal surgery in order to improve postoperative oxygen saturation and lung function. We aim to test whether speaking loudly from a given text improve postoperative oxygen saturation and ventilation. 50 patients will be investigated in a randomized controlled trial with cross-over design starting either with positive expiratory pressure therapy (10 times 3 inspiration and expiration to positive expiratory pressure) or with speaking loudly from a given text.
Eligibility
Inclusion criteria
* Performed abdominal surgery within 2 days at the departments of surgery, urology or gynecology at Umeå university hospital
Exclusion criteria
* Patients referred to ICU because of immediate postoperative complications. * Patients who are unable to perform the study.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Oxygen saturation after speaking aloud | At day 1 or 2 after surgery | Oxygen saturation (SaO2) at 7 minutes after speaking aloud compared with positive expiratory pressure therapy |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Ventilation after speaking aloud | At day 1 or 2 after surgery | Transcutaneous carbon dioxide partial pressure after speaking aloud compared with positive expiratory pressure therapy |
Countries
Sweden