Kidney Transplant
Conditions
Brief summary
Researchers are trying to determine if exercise will improve health and strength in kidney transplant patients.
Interventions
OTHERExercise Program
Perform endurance (treadmill or cycle ergometer), strength (weight resistance), and flexibility training twice a week for a period of one hour per session, for a total of 16 sessions.
Sponsors
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Mayo Clinic
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
SUPPORTIVE_CARE
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Patients age ≥ 18 years who have received a KT and have a functioning allograft
Exclusion criteria
* Neuropsychiatric condition causing patient to be unable to provide consent * Recipient of a combined organ transplant
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Change in frailty status | Two months | Frailty will be determined by Frailty Phenotype (FP) or Short Physical Performance Battery (SPPB) scores. FP is determined by the presence of 3 or more of the following: slowness (measured by gait speed), exhaustion (measured via self-report), weakness (measured by hand grip strength), low physical activity level (measured via self-report), and wasting (measured via self-report or by tracking changes in weight). The SPPB consists of a gait speed test, balance testing, and repeated chair stands. A score less than or equal to 10 will be considered frail. |
Countries
United States
Outcome results
None listed