The Study of the Efficacy of Laser Acupuncture on Osteoarthritis Knees by Using Magnetic Resonance Imaging, Clinical Evaluation, and Movement Analysis

Status

UNKNOWN

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT04275427

Enrollment

Registered

2020-02-19

Start date

2019-01-01

Completion date

2021-01-01

Last updated

2020-02-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Osteoarthritis, Knee

Brief summary

To study the efficacy of laser acupuncture on osteoarthritis (OA) knee patients by magnetic resonance imaging (MRI), clinical evaluation and movement analysis.

Detailed description

The Kellgren-Lawrence (KL) grading scheme for OA knee Patient selecting flow Age: 20-70 year old Grade II-III knee OA Exlusion: Trauma history/ Space claustrophobia /Severe chronic disease/ Malignancy Pregnancy Study Cases 40 Randomize Pre-treatment MRI (to evaluate grade of OA knee/ the T2 signal of the cartilage), MRS (baseline glutamate), Movement analysis(sit to stand), Maximum strength ratio of Quadriceps/Hamstring WOMAC Post-treatment evaluation laser therapy Modality: LA-400 Treatment protocol of low level laser * 40mW, 50Hz, 808nm (invisible light) , 15min * The effect of laser acupuncture is dose dependent Effect of Laser Therapy on Chronic Osteoarthritis of the Knee in Older SubjectsJ Lasers Med Sci. 2016 Spring; 7(2): 112-119 * 830nm is an effective form of treatment for chronic knee pain caused by knee osteoarthritis. Low Level Laser Therapy for chronic knee joint pain patientsLaser Ther. 2014 Dec 27; 23(4): 273-277 * Duration: 2 weeks Frequency: 3 times/week * Control group: no treatment Acupuncture point: EX- LE-5, EX-EL 2, SP10

Interventions

DEVICELA-400 laser acupuncture

low level laser

Study design

Allocation

NON_RANDOMIZED

Intervention model

SINGLE_GROUP

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

20 Years to 70 Years

Healthy volunteers

Inclusion criteria

* Kellgren-Lawrence grade II \ III

Exclusion criteria

* Trauma history/ Space claustrophobia/ Severe chronic disease/Malignancy Pregnancy

Design outcomes

Primary

Measure	Time frame	Description
difference on MRI post- versus pre- treatment	2 weeks	compare the apparent diffusion coefficient (ADC) value post- and pre- treatment, suppose that the higher the value, the less inflammation in target tissue

Secondary

Measure	Time frame	Description
Improve stability on movement analysis	2 weeks	Calculate the area of center of posture (COP) during the movement. Suppose that the lower value, the higher stability.

Other

Measure	Time frame	Description
decreased WOMAC score	2 weeks	The Western Ontario and McMaster Universities Osteoarthritis Index, pain(0-20), stiffness(0-8), functional limitation(0-68). The higher the score, the worse the pain, stiffness and limitation

Countries

Taiwan

Contacts

Primary ContactChing Wen Huang, M.D.

b318is2002@yahoo.com.tw886-2-28332211

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026