Skip to content

Dentin Bridge Formation After Indirect Pulp Capping With Bioactive Glass Incorporated in Resin Composite and Its Adhesive in Comparison With Light Cured Calcium Hydroxide

Clinical Response of Human Pulps Capped With Bioactive Glass Incorporated in Resin Composite and Adhesive

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT04274920
Enrollment
36
Registered
2020-02-18
Start date
2017-03-01
Completion date
2018-07-01
Last updated
2020-02-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pulp Disease, Dental, Dental Caries

Brief summary

The aim of this study is to evaluate the effect of application of bioactive glass in different protocols on the formation of dentin bridge after indirect pulp capping using resin composite with its adhesive both are containing bioactive glass.

Interventions

Bioactive glass was incorporated in resin composite and its adhesive

OTHERLight cured calcium hydroxide

Light cured calcium hydroxide

Sponsors

Al-Azhar University
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE (Subject, Outcomes Assessor)

Eligibility

Sex/Gender
ALL
Age
18 Years to 35 Years
Healthy volunteers
Yes

Inclusion criteria

* Active carious lesion in deep dentin of molars. * Absence of cavitated lesions at the buccal or lingual surfaces as determined by clinical and radiographic examination. * Absence of clinical diagnosis of pulp exposure, fistula, swelling of periodontal tissues, and abnormal tooth mobility; * Absence of clinical symptoms of irreversible pulpitis, such as spontaneous pain or sensitivity to pressure; * The extension of the carious lesion should be such that complete caries removal would risk pulp exposure, as determined by clinical and radiographic assessment; * Absence of radiolucencies at the interradicular or periapical regions, or thickening of the periodontal spaces, that would indicate the presence of irreversible pulp pathologies or necrosis; * Absence of internal or external root resorption. * Co-operative patients approving the trial.

Exclusion criteria

* Patients with systemic medical conditions * pregnant females * Teeth with spontaneous pain or sensitivity to percussion. * Teeth with periodontal lesions, internal or external root resorption, mobility of tooth, sinus opening, or abscessed tooth. * Radiographic examination revealed, interrupted or broken lamina dura, widened periodontal ligament space, periapical radiolucency.

Design outcomes

Primary

MeasureTime frameDescription
Change of dentine thicknessbaseline, one month, 3 months and 6 monthsThickness in millimeters using CBCT

Countries

Egypt

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026