Optical Guided Surgery
Conditions
Brief summary
Head and neck cancer has an incidence of 600,000 cases per year worldwide (6th among cancers) and cause 380,000 death per year. Surgical resection is guided by the surgeon's inspection and palpation of the tumor. The prognosis of patients depends on the quality of the lesion's resection. The ENDOSWIR dispositive developed by engineers of Atomic Energy Comity of Grenoble allows for reliable and accurate analysis of tumor margins. The camera provides a spectral analysis of the tissues according to their composition. We want to show that the prognosis of patients is improved by the use of this device. For that we need to prove first that it is not toxic for tissue analysis.
Detailed description
ENDOSWIR dispositive is a InGaAs (Indium Gallium Arsenide) camera working at ambient temperature. The light is a quartz-tungstene-halogeno (QTH) source and the collected beam is filtered to illuminate in different precise wavelength bands in the short wave domain. We will use it on tonsil tissue just after tonsillectomy and just before the histological analysis.
Interventions
DEVICEEndoSWIR
Exposition of the respected tissues to the camera
Sponsors
Institut National de la Santé et de la Recherche Médicale, Institute for Advanced Biosciences
Commissariat A L'energie Atomique
Lynred
University Hospital, Grenoble
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Tonsillectomy
Exclusion criteria
* suspicion of Head-and neck cancer
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Tissue integrity | 1 day | Histological score : evaluation of cellular cohesion and denaturation of epithelial cells and conjunctive support tissue |
Countries
France
Contacts
Primary ContactChristian RIGHINI
Backup ContactNoémie DUTRIEUX
Outcome results
None listed