Influence of Brief Supportive Psychotherapy on Major Adverse Cardiovascular Events, Neutrophil-lymphocytes Ratio and Psychological Symptoms in Acute Coronary Syndrome in Intensive Cardiac Care Unit

Influence of Brief Supportive Psychotherapy on Major Adverse Cardiovascular Events, Neutrophil-lymphocytes Ratio and Psychological Symptoms in Acute Coronary Syndrome Patients in Intensive Cardiac Care Unit

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT04274205

Acronym

Supportive

Enrollment

Registered

2020-02-18

Start date

2019-04-18

Completion date

2019-07-30

Last updated

2020-02-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute Coronary Syndrome, Brief Supportive Psychotherapy, Intensive Cardiac Care Unit

Keywords

Brief supportive psychotherapy, acute coronary syndrome, major adverse cardiovascular events, neutrophil-lymphocytes ratio, psychological symptoms

Brief summary

There was no MACE in both groups, but there was stroke-major adverse vascular event lower in brief supportive psychotherapy group. There was neutrophil-lymphocytes ratio change better in brief supportive psychotherapy group and significantly in acute coronary syndrome patients without chronic heart failure or coronary arterial disease, also there was psychological symptom (depression) change better in brief supportive psychotherapy and significantly in acute coronary syndrome patients with chronic heart failure or coronary arterial disease.

Interventions

OTHERIntervention group

Brief supportive psychotherapy

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

NONE

Intervention model description

Two groups Acute coronary syndrome group who got brief psychotherapy in five session in 5 days.. 30 minutes in 1 session Acute coronary syndrome group who did not get brief supportive psychotherapy as control Double opened RCT

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* acute coronary syndrome * 》 18 years old * have got pharmacological treatment in cardiology standard with or without anxiolytic drug and had got or had not yet got PCI * be able to communicate and ready to have interview, fill the questioners and psychotherapy

Exclusion criteria

* stroke * cardiogenic shock at admission time * psychosis * reject to involve in study

Design outcomes

Primary

Measure	Time frame	Description
Major adverse cardiovascular events	5 days	Fatal arrhytmia, recurrent myocardial infarction, cardiogenic shock, death

Secondary

Measure	Time frame	Description
Neutrophil-lymphocytes ratio	5 days	Pre-post measure
Psychological symptoms (Hospital anxiety depression scale)	5 days	Pre-post measure

Countries

Indonesia

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026