Liver Cancer
Conditions
Keywords
prevention, education
Brief summary
This study proposes to bridge the gap between evidence and action and combat rising liver cancer rates attributed to Hepatitis B and C infection in Philadelphia by identifying neighborhoods with higher than expected rates of liver cancer and related risk factors and administering an educational intervention about liver cancer and neighborhood health in those communities, working with existing community partners at Fox Chase Cancer Center.
Interventions
BEHAVIORALLIVE-R Life Education
A health educator will present participants with a 30-minute PowerPoint presentation containing educational information about liver cancer risk, screening, prevention, symptoms, and treatments, as well as introduce the concept of neighborhood health (e.g., rates of liver cancer and related risk factors in a census tract and how that might influence individual cancer risk).
Sponsors
Pennsylvania Department of Health
Fox Chase Cancer Center
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
PREVENTION
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
* Speaks/reads English * Lives in Philadelphia or receives healthcare at a community partner site in Philadelphia
Exclusion criteria
* None
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Change in Mean Liver Cancer Knowledge | Baseline, 30 minutes | Liver cancer knowledge will be measured through four true/false items. Responses will be summed for a total liver cancer knowledge score. Score ranges run from 0-4, with higher scores indicating more knowledge. Change in knowledge is measured by subtracting baseline knowledge score from the post-intervention knowledge score. Change scores may range from -4 to 4, with positive scores indicating an increase in knowledge. Higher positive scores indicate a larger increase in knowledge. |
| Change in General Interest in Learning About Neighborhood Health | Baseline, 30 minutes | General interest in learning about neighborhood health will be measured through a single item asking, on a scale from strongly agree to strongly disagree, whether the participant would like to learn about liver cancer in their own neighborhood. Scores range from 1 to 5, with higher scores indicating more interest in learning about neighborhood health from a healthcare provider. Change in interest is measured by subtracting the baseline interest score from the post-intervention interest score. Change scores may range from -4 to 4, with positive scores indicating an increase in interest. Higher positive scores indicate a larger increase in interest. |
| Change in Interest in Learning About Neighborhood Health From a Healthcare Provider | Baseline, 30 minutes | Interest in learning about neighborhood health from a healthcare provider will be measured through a single item asking, on a scale from strongly agree to strongly disagree, whether the participant would like to learn about liver cancer in their own neighborhood from their doctor. Scores range from 1 to 5, with higher scores indicating more interest in learning about neighborhood health from a healthcare provider. Change in interest is measured by subtracting the baseline interest score from the post-intervention interest score. Change scores may range from -4 to 4, with positive scores indicating an increase in interest. Higher positive scores indicate a larger increase in interest. |
| Change in Interest in Learning About Neighborhood Health From Other Sources | Baseline, 30 minutes | Interest in learning about neighborhood health from other sources will be measured through a single item asking, on a scale from strongly agree to strongly disagree, whether the participant would like to learn about liver cancer in their own neighborhood from non-medical sources (e.g., website or brochure). Scores range from 1 to 5, with higher scores indicating more interest in learning about neighborhood health from other sources. Change in interest is measured by subtracting the baseline interest score from the post-intervention interest score. Change scores may range from -4 to 4, with positive scores indicating an increase in interest. Higher positive scores indicate a larger increase in interest. |
| Change in Interest in Discussing High Liver Cancer Risk With a Healthcare Provider | Baseline, 30 minutes | Interest in discussing high liver cancer risk with a healthcare provider will be measured through a single item asking, on a scale from strongly agree to strongly disagree, whether the participant would be likely to discuss their liver cancer risk with a doctor if they learned they lived in a high-risk area. Scores range from 1 to 5, with higher scores indicating more interest in discussing liver cancer risk with a healthcare provider. Change in interest is measured by subtracting the baseline interest score from the post-intervention interest score. Change scores may range from -4 to 4, with positive scores indicating an increase in interest. Higher positive scores indicate a larger increase in interest. |
| Change in Outcome Expectancies for Learning About Neighborhood Health - Patient Behavior | Baseline, 30 minutes | Patient outcome expectancies for learning about neighborhood health will be measured through a single item asking, on a scale from 0 (not at all) to 10 (very much), whether learning about neighborhood health will help the participant make health decisions. Higher scores indicate more positive expectations. Change in outcomes expectancies is measured by subtracting the baseline score from the post-intervention score. Change scores may range from -10 to 10, with positive scores indicating an increase in outcome expectancies. Higher positive scores indicate a larger increase in expectations. |
| Change in Outcome Expectancies for Learning About Neighborhood Health - Provider Behavior | Baseline, 30 minutes | Provider outcome expectancies for learning about neighborhood health will be measured through a single item asking, on a scale from 0 (not at all) to 10 (very much), whether learning about neighborhood health will help the participant's healthcare provider make health decisions for them. Higher scores indicate more positive expectations. Change in outcome expectancies is measured by subtracting the baseline score from the post-intervention score. Change scores may range from -10 to 10, with positive scores indicating an increase in outcome expectancies. Higher positive scores indicate a larger increase in expectations. |
| Change in Intentions About Communicating With Healthcare Provider - Neighborhood Prevalence of Liver Cancer | Baseline, 30 minutes | intentions about communicating with healthcare provider about neighborhood liver cancer will be measured through a single item asking, on a scale from very likely to not at all likely, how likely the participant is to discuss liver cancer in their neighborhood with their healthcare provider over the next 12 months. Scores range from 1 to 5, with higher scores indicating higher likelihood of talking to a healthcare provider. Change in intentions is measured by subtracting the baseline score from the post-intervention score. Change scores may range from -4 to 4, with positive scores indicating an increase in intentions. Higher positive scores indicate a larger increase in intentions. |
| Change in Intentions About Communicating With Healthcare Provider - Liver Cancer Screening | Baseline, 30 minutes | intentions about communicating with healthcare provider about liver cancer screening will be measured through a single item asking, on a scale from very likely to not at all likely, how likely the participant is to discuss liver cancer screening with their healthcare provider over the next 12 months. Scores range from 1 to 5, with higher scores indicating higher likelihood of talking to a healthcare provider. Change in intentions is measured by subtracting the baseline score from the post-intervention score. Change scores may range from -4 to 4, with positive scores indicating an increase in intentions. Higher positive scores indicate a larger increase in intentions. |
| Change in Intentions About Communicating With Healthcare Provider - Liver Cancer Risk | Baseline, 30 minutes | intentions about communicating with healthcare provider about liver cancer risk will be measured through a single item asking, on a scale from very likely to not at all likely, how likely the participant is to discuss their personal risk factors for liver cancer with their healthcare provider over the next 12 months. Scores range from 1 to 5, with higher scores indicating higher likelihood of talking to a healthcare provider. Change in intentions is measured by subtracting the baseline score from the post-intervention score. Change scores may range from -4 to 4, with positive scores indicating an increase in intentions. Higher positive scores indicate a larger increase in intentions. |
Countries
United States
Participant flow
Participants by arm
| Arm | Count |
|---|---|
| Liver Cancer Education LIVE-R Life Education: A health educator will present participants with a 30-minute PowerPoint presentation containing educational information about liver cancer risk, screening, prevention, symptoms, and treatments, as well as introduce the concept of neighborhood health (e.g., rates of liver cancer and related risk factors in a census tract and how that might influence individual cancer risk). | 67 |
| Total | 67 |
Baseline characteristics
| Characteristic | Liver Cancer Education |
|---|---|
| Age, Continuous | 50.25 years STANDARD_DEVIATION 18.9 |
| Ethnicity (NIH/OMB) Hispanic or Latino | 29 Participants |
| Ethnicity (NIH/OMB) Not Hispanic or Latino | 38 Participants |
| Ethnicity (NIH/OMB) Unknown or Not Reported | 0 Participants |
| Race (NIH/OMB) American Indian or Alaska Native | 0 Participants |
| Race (NIH/OMB) Asian | 1 Participants |
| Race (NIH/OMB) Black or African American | 22 Participants |
| Race (NIH/OMB) More than one race | 2 Participants |
| Race (NIH/OMB) Native Hawaiian or Other Pacific Islander | 0 Participants |
| Race (NIH/OMB) Unknown or Not Reported | 21 Participants |
| Race (NIH/OMB) White | 21 Participants |
| Region of Enrollment United States | 67 participants |
| Sex: Female, Male Female | 50 Participants |
| Sex: Female, Male Male | 17 Participants |
Adverse events
| Event type | EG000 affected / at risk |
|---|---|
| deaths Total, all-cause mortality | 0 / 67 |
| other Total, other adverse events | 0 / 67 |
| serious Total, serious adverse events | 0 / 67 |
Outcome results
Primary
Change in General Interest in Learning About Neighborhood Health
General interest in learning about neighborhood health will be measured through a single item asking, on a scale from strongly agree to strongly disagree, whether the participant would like to learn about liver cancer in their own neighborhood. Scores range from 1 to 5, with higher scores indicating more interest in learning about neighborhood health from a healthcare provider. Change in interest is measured by subtracting the baseline interest score from the post-intervention interest score. Change scores may range from -4 to 4, with positive scores indicating an increase in interest. Higher positive scores indicate a larger increase in interest.
Time frame: Baseline, 30 minutes
| Arm | Measure | Value (MEAN) | Dispersion |
|---|---|---|---|
| Liver Cancer Education | Change in General Interest in Learning About Neighborhood Health | -1.81 score on a scale | Standard Deviation 1.5 |
Primary
Change in Intentions About Communicating With Healthcare Provider - Liver Cancer Risk
intentions about communicating with healthcare provider about liver cancer risk will be measured through a single item asking, on a scale from very likely to not at all likely, how likely the participant is to discuss their personal risk factors for liver cancer with their healthcare provider over the next 12 months. Scores range from 1 to 5, with higher scores indicating higher likelihood of talking to a healthcare provider. Change in intentions is measured by subtracting the baseline score from the post-intervention score. Change scores may range from -4 to 4, with positive scores indicating an increase in intentions. Higher positive scores indicate a larger increase in intentions.
Time frame: Baseline, 30 minutes
Population: Four participants did not respond to this item at pre- or post-survey.
| Arm | Measure | Value (MEAN) | Dispersion |
|---|---|---|---|
| Liver Cancer Education | Change in Intentions About Communicating With Healthcare Provider - Liver Cancer Risk | 0.35 score on a scale | Standard Deviation 0.97 |
Primary
Change in Intentions About Communicating With Healthcare Provider - Liver Cancer Screening
intentions about communicating with healthcare provider about liver cancer screening will be measured through a single item asking, on a scale from very likely to not at all likely, how likely the participant is to discuss liver cancer screening with their healthcare provider over the next 12 months. Scores range from 1 to 5, with higher scores indicating higher likelihood of talking to a healthcare provider. Change in intentions is measured by subtracting the baseline score from the post-intervention score. Change scores may range from -4 to 4, with positive scores indicating an increase in intentions. Higher positive scores indicate a larger increase in intentions.
Time frame: Baseline, 30 minutes
| Arm | Measure | Value (MEAN) | Dispersion |
|---|---|---|---|
| Liver Cancer Education | Change in Intentions About Communicating With Healthcare Provider - Liver Cancer Screening | 0.67 score on a scale | Standard Deviation 1.24 |
Primary
Change in Intentions About Communicating With Healthcare Provider - Neighborhood Prevalence of Liver Cancer
intentions about communicating with healthcare provider about neighborhood liver cancer will be measured through a single item asking, on a scale from very likely to not at all likely, how likely the participant is to discuss liver cancer in their neighborhood with their healthcare provider over the next 12 months. Scores range from 1 to 5, with higher scores indicating higher likelihood of talking to a healthcare provider. Change in intentions is measured by subtracting the baseline score from the post-intervention score. Change scores may range from -4 to 4, with positive scores indicating an increase in intentions. Higher positive scores indicate a larger increase in intentions.
Time frame: Baseline, 30 minutes
Population: One participants did not answer this item at pre- or post-survey
| Arm | Measure | Value (MEAN) | Dispersion |
|---|---|---|---|
| Liver Cancer Education | Change in Intentions About Communicating With Healthcare Provider - Neighborhood Prevalence of Liver Cancer | 0.79 score on a scale | Standard Deviation 1.06 |
Primary
Change in Interest in Discussing High Liver Cancer Risk With a Healthcare Provider
Interest in discussing high liver cancer risk with a healthcare provider will be measured through a single item asking, on a scale from strongly agree to strongly disagree, whether the participant would be likely to discuss their liver cancer risk with a doctor if they learned they lived in a high-risk area. Scores range from 1 to 5, with higher scores indicating more interest in discussing liver cancer risk with a healthcare provider. Change in interest is measured by subtracting the baseline interest score from the post-intervention interest score. Change scores may range from -4 to 4, with positive scores indicating an increase in interest. Higher positive scores indicate a larger increase in interest.
Time frame: Baseline, 30 minutes
Population: Three participants did not respond to this item at pre- or post-survey.
| Arm | Measure | Value (MEAN) | Dispersion |
|---|---|---|---|
| Liver Cancer Education | Change in Interest in Discussing High Liver Cancer Risk With a Healthcare Provider | -1.58 score on a scale | Standard Deviation 1.69 |
Primary
Change in Interest in Learning About Neighborhood Health From a Healthcare Provider
Interest in learning about neighborhood health from a healthcare provider will be measured through a single item asking, on a scale from strongly agree to strongly disagree, whether the participant would like to learn about liver cancer in their own neighborhood from their doctor. Scores range from 1 to 5, with higher scores indicating more interest in learning about neighborhood health from a healthcare provider. Change in interest is measured by subtracting the baseline interest score from the post-intervention interest score. Change scores may range from -4 to 4, with positive scores indicating an increase in interest. Higher positive scores indicate a larger increase in interest.
Time frame: Baseline, 30 minutes
Population: Two participants did not answer this item at pre- or post-test.
| Arm | Measure | Value (MEAN) | Dispersion |
|---|---|---|---|
| Liver Cancer Education | Change in Interest in Learning About Neighborhood Health From a Healthcare Provider | -0.95 score on a scale | Standard Deviation 1.46 |
Primary
Change in Interest in Learning About Neighborhood Health From Other Sources
Interest in learning about neighborhood health from other sources will be measured through a single item asking, on a scale from strongly agree to strongly disagree, whether the participant would like to learn about liver cancer in their own neighborhood from non-medical sources (e.g., website or brochure). Scores range from 1 to 5, with higher scores indicating more interest in learning about neighborhood health from other sources. Change in interest is measured by subtracting the baseline interest score from the post-intervention interest score. Change scores may range from -4 to 4, with positive scores indicating an increase in interest. Higher positive scores indicate a larger increase in interest.
Time frame: Baseline, 30 minutes
| Arm | Measure | Value (MEAN) | Dispersion |
|---|---|---|---|
| Liver Cancer Education | Change in Interest in Learning About Neighborhood Health From Other Sources | -0.90 score on a scale | Standard Deviation 1.72 |
Primary
Change in Mean Liver Cancer Knowledge
Liver cancer knowledge will be measured through four true/false items. Responses will be summed for a total liver cancer knowledge score. Score ranges run from 0-4, with higher scores indicating more knowledge. Change in knowledge is measured by subtracting baseline knowledge score from the post-intervention knowledge score. Change scores may range from -4 to 4, with positive scores indicating an increase in knowledge. Higher positive scores indicate a larger increase in knowledge.
Time frame: Baseline, 30 minutes
Population: Five participants skipped the knowledge items on either the pre-test or the post-test.
| Arm | Measure | Value (MEAN) | Dispersion |
|---|---|---|---|
| Liver Cancer Education | Change in Mean Liver Cancer Knowledge | 1.26 score on a scale | Standard Deviation 1.09 |
Primary
Change in Outcome Expectancies for Learning About Neighborhood Health - Patient Behavior
Patient outcome expectancies for learning about neighborhood health will be measured through a single item asking, on a scale from 0 (not at all) to 10 (very much), whether learning about neighborhood health will help the participant make health decisions. Higher scores indicate more positive expectations. Change in outcomes expectancies is measured by subtracting the baseline score from the post-intervention score. Change scores may range from -10 to 10, with positive scores indicating an increase in outcome expectancies. Higher positive scores indicate a larger increase in expectations.
Time frame: Baseline, 30 minutes
Population: One participant did not answer this item at pre- or post-survey
| Arm | Measure | Value (MEAN) | Dispersion |
|---|---|---|---|
| Liver Cancer Education | Change in Outcome Expectancies for Learning About Neighborhood Health - Patient Behavior | 0.83 score on a scale | Standard Deviation 2.58 |
Primary
Change in Outcome Expectancies for Learning About Neighborhood Health - Provider Behavior
Provider outcome expectancies for learning about neighborhood health will be measured through a single item asking, on a scale from 0 (not at all) to 10 (very much), whether learning about neighborhood health will help the participant's healthcare provider make health decisions for them. Higher scores indicate more positive expectations. Change in outcome expectancies is measured by subtracting the baseline score from the post-intervention score. Change scores may range from -10 to 10, with positive scores indicating an increase in outcome expectancies. Higher positive scores indicate a larger increase in expectations.
Time frame: Baseline, 30 minutes
Population: Two participants did not respond to this item at pre- or post-survey
| Arm | Measure | Value (MEAN) | Dispersion |
|---|---|---|---|
| Liver Cancer Education | Change in Outcome Expectancies for Learning About Neighborhood Health - Provider Behavior | -0.77 score on a scale | Standard Deviation 2.4 |