Lymphoma
Conditions
Keywords
All types of lymphoma
Brief summary
This trial studies how well a mind-body intervention works in improving overall quality of life in adolescents and young adults with lymphoma. A meditation based mind-body intervention may help lower distress, depressive symptoms, and anxiety in adolescents and young adults coping with lymphoma.
Detailed description
PRIMARY OBJECTIVE: I. Examine the feasibility of the mind-body intervention in adolescents and young adults (AYAs) with lymphoma. SECONDARY OBJECTIVE: I. Establish the initial intervention efficacy regarding psychological distress and cancer symptoms (tertiary objective) relative to an attention control (AC) group. EXPLORATORY OBJECTIVE: I. Explore mediation (e.g., mindfulness, compassion, social connection, inflammatory processes) and moderation (e.g., demographic and medical factors) of the intervention effects. OUTLINE: Patients are randomized to 1 of 2 groups. GROUP I: Patients attend meditation group sessions over 75 minutes once weekly for up to 5 weeks. GROUP II: Patients attend educational group sessions over 75 minutes once weekly for up to 5 weeks. After completion of study intervention, patients are followed at 6 and 12 weeks.
Interventions
OTHEREducational Intervention
Attend educational sessions
OTHERMeditation Therapy
Attend meditation sessions
OTHERQuestionnaire Administration
Ancillary studies
Sponsors
M.D. Anderson Cancer Center
National Cancer Institute (NCI)
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
SUPPORTIVE_CARE
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 39 Years
Healthy volunteers
No
Inclusion criteria
* Participants between the ages of 18-39 diagnosed within 6 months with stage I-IV Lymphoma (all types) * Eastern Cooperative Oncology Group (ECOG) performance status of 2 or below * Having access to the internet * Able to read, write and speak English
Exclusion criteria
* Major psychiatric or cognitive deficits that would impede the completion of self-report instruments as deemed by the clinical team * Regular (self-defined) participation in psychotherapy or a formal cancer support group
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Mind-body intervention in (AYAs) Adolescents and Young Adults with Lymphoma Questionnaire | Up to 12 weeks | We will examine preliminary evidence of intervention efficacy. Meaning and Purpose (1-5) Strongly Disagree 1- Disagree 2, Neither agree or disagree 3, Agree 4, Strongly agree 5. Day-to-Day Experiences (1-6) Almost Always-1, Very frequently-2, Somewhat Frequently -3, Somewhat Infrequently-4, Very Infrequently-5, Almost Never 6 |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Psychological distress and cancer symptoms (tertiary objective) relative to an attention control (AC) group Questionnaire | Up to 12 weeks | We will examine preliminary evidence of intervention efficacy. Meaning and Purpose (1-5) Strongly Disagree 1- Disagree 2, Neither agree or disagree 3, Agree 4, Strongly agree 5. Day-to-Day Experiences (1-6) Almost Always-1, Very frequently-2, Somewhat Frequently -3, Somewhat Infrequently-4, Very Infrequently-5, Almost Never 6 |
Countries
United States
Contacts
PRINCIPAL_INVESTIGATORKathrin Milbury
M.D. Anderson Cancer Center
Outcome results
None listed