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End-range Mobilization on Knee Osteoarthritis

End-range Mobilization Effecting Pain and Physical Function in the Management of Knee Osteoarthritis

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT04270253
Enrollment
30
Registered
2020-02-17
Start date
2020-02-12
Completion date
2020-05-12
Last updated
2020-11-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Osteo Arthritis Knee

Keywords

Musculoskeletal Manipulations, Osteoarthritis, Knee, Conservative Treatment

Brief summary

Different manual therapy techniques and conservative therapy have been used separately for alleviation of pain and improvement of physical function in patients with knee osteoarthritis (KOA). However, no study has reported the effect of combination of these treatment modalities in the management of KOA. The aim of this study was to investigate the effect of end-range mobilization added to conservative therapy versus conservative therapy alone on decrease of pain and improvement of functional status in KOA.

Detailed description

Knee osteoarthritis (KOA) is a musculoskeletal condition affecting older people. It is characterized by pain and loss of physical function, which has a negative impact on patients' quality of life. The different international guidelines recommend several non-invasive treatment modalities for the management of KOA. Conservative therapy including land-based exercises, aquatic exercises, Transcutaneous Electro Neuro Stimulation (TENS) therapy and balneotherapy has been reported positively in the management of patients with KOA (1, 2). Manual therapy is also a preferred treatment modality with the aim of alleviation of pain, improvement of joint mobility and therefore the physical condition (1, 2). Out of manual therapy techniques, end-range mobilization is a well applied treatment technique in the management of different musculoskeletal conditions (3). Till date, the effect of end-range mobilization has not been investigated so far in knee OA. Therefore, the aim of this study was to investigate the effect of end-range mobilization added to conservative therapy versus conservative therapy alone on decrease of pain and improvement of functional status in KOA.

Interventions

Conservative therapy including aquatic exercises, land-based exercises, balneotherapy, TENS therapy

PROCEDUREManual therapy

End-range mobilization

Sponsors

University of Pecs
Lead SponsorOTHER

Study design

Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
60 Years to 90 Years
Healthy volunteers
No

Inclusion criteria

* KOA according to the American College of Rheumatology * categorization as End Of Range Problem based on Maitland's classification. * at least half year existing and at least 3 pain scores measured with Visual Analogue Scale (VAS) during weight-bearing activities * bilateral, moderate-to-severe symptomatic tibiofemoral knee OA with radiographic evidence * at least 90 degree passive knee flexion range * sufficient mental status

Exclusion criteria

* acute inflammation of the knee * intraarticular injections within the last 3 months * total knee replacement in the opposite side * class II. obesity (body mass index, BMI\>35kg/m2) * severe degenerative lumbar spine disease (e.g. spondylolisthesis) * systemic inflammatory arthritic or neurological condition * physiotherapy and other balneotherapy attendance within 6 months * contraindication for conservative and manual therapy * unstable heart condition * complex regional pain syndrome

Design outcomes

Primary

MeasureTime frameDescription
general pain intensityat the end of the 3-week rehabilitationmeasuring of general pain intensity with Visual Analogue Scale

Secondary

MeasureTime frameDescription
pain intensity during getting in carat the end of the 3-week rehabilitationmeasuring of pain intensity during getting in car with Visual Analogue Scale
pain intensity during turning while walkingat the end of the 3-week rehabilitationmeasuring of pain intensity during turning while walking with Visual Analogue Scale
pain intensity during stair descendingat the end of the 3-week rehabilitationmeasuring of pain intensity during stair descending with Visual Analogue Scale
pain intensity during getting up from a chairat the end of the 3-week rehabilitationmeasuring of pain intensity during getting up from a chair with Visual Analogue Scale
Quadriceps and hamstring muscles peak muscle forceat the end of the 3-week rehabilitationQuadriceps and hamstring muscles peak muscle force of both knees
6-minute walk testat the end of the 3-week rehabilitation6-minute walk test measuring functional capacity
Timed Up and Go testat the end of the 3-week rehabilitationTimed Up and Go test measuring functional capacity
Flexion and extension passive range of motionat the end of the 3-week rehabilitationFlexion and extension passive range of motion of the tibiofemoral joint

Countries

Hungary

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026