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Lactoferrin Efficacy Versus Ferrous Sulfate in Treatment of Patients With Iron Deficiency Anemia

Lactoferrin Efficacy Versus Ferrous Sulfate in Treatment of Patients With Iron Deficiency Anemia

Status
Completed
Phases
Phase 4
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT04267653
Enrollment
96
Registered
2020-02-13
Start date
2018-01-01
Completion date
2018-10-30
Last updated
2020-02-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Iron Deficiency Anemia Treatment

Keywords

Iron deficiency anemia, Lactoferrin, Ferrous sulfate

Brief summary

Lactoferrin (Lf) is a mammalian cationic iron binding glycoprotein belonging to the transferrin family which was discovered 70 years ago, and isolated simultaneously from human and bovine milks in 1960. It is widely distributed in all biological fluids and is also expressed by immune cells, which release it under stimulation by pathogens

Interventions

treatment for 30 days

DRUGFerrous Sulfate

treatment for 30 days

Sponsors

Assiut University
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Subject)

Eligibility

Sex/Gender
ALL
Age
2 Years to 15 Years
Healthy volunteers
No

Inclusion criteria

all patients with iron deficiency anemia from 2 to 15 years old \-

Exclusion criteria

* Anemia rather than iron deficiency anemia. * Family history of blood disease. * Patients with thalassemia trait. * Patients with chronic illness.

Design outcomes

Primary

MeasureTime frameDescription
comparison of efficacy of lactoferrin versus ferrous sulfate tharapy in treatment of patients with iron deficiency anemia.30 daysComplete blood count will be done before and after therapy to detect the effect of the therapy on serum hemoglobin(g/d)
Comparison of efficacy of lactoferrin versus ferrous sulfate tharapy in treatment of patients with iron deficiency anemia.30 daysTotal serum iron(ug/d) will be done before and after therapy to detect effect of the therapy on total serum iron level (ug/d)

Countries

Egypt

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026