Pregnancy Related
Conditions
Keywords
snakehead fish cookies, intrauterine fetal growth, low birth weight, randomized controlled trial, protein supplementation
Brief summary
This study was randomized controlled trial study whose subjects were pregnant women in Sleman District, Yogyakarta, Indonesia. The aims of this study were to make snakehead fish cookies formula which can be well accepted by pregnant women and to observed its effect on fetal growth and birth weight and length. It was hypothesized that snakehead fish cookies could prevent intrauterine fetal growth (IUGR) and low birth weight (LBW). Subjects on this study were randomly allocated into two groups which were treatment and control group. Subjects in treatment group were given snakehead fish cookies, while subject in control group received standard cookies. The intervention period lasted until subjects delivered their babies.
Detailed description
Subjects were enrolled from Public Health Center (puskesmas) in Sleman District, Yogyakarta Province, Indonesia. Subjects were being explained about the study intervention and were given informed consent as an approval of joining this study. The intervention was given everyday as much as 75g cookies for several weeks period (until delivery). Examination on fetal growth was done every month for each subjects. Birth weight and length were collected after delivery from child health book record.
Interventions
DIETARY_SUPPLEMENTcookies
Either snakehead fish cookies or standard cookies were given to subjects 75g per day.
Sponsors
Indonesia-MoH
Gadjah Mada University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
TRIPLE (Subject, Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
FEMALE
Age
No minimum to 25 Years
Healthy volunteers
Yes
Inclusion criteria
1. second and third trimester gestational age, 2. lower-class family with income under Sleman District minimum wage in 2019 (\< 1,701,000 Rupiah), 3. pregnant women of under 25 years old, and 4. high school graduate or below
Exclusion criteria
1. suffering from anemia, 2. experiencing preeclampsia, 3. having multiple gestational, and 4. allergic to fish, eggs, and chocolate.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Birth weight | immediately after the baby is born | Birth weight of the baby |
| Birth length | immediately after the baby is born | Birth length of the baby |
| Estimated fetal weight (EFW) | change from baseline EFW after 1 month | We measured EFW monthly using 2D ultrasonography (USG) for each subjects |
| Biparietal diameter (BPD) | change from baseline BPD after 1 month | We measured BPD monthly using 2D ultrasonography (USG) for each subjects |
| Abdominal circumference (AC) | change from baseline AC after 1 month | We measured AC monthly using 2D ultrasonography (USG) for each subjects |
| Femur length (FL) | change from baseline FL after 1 month | We measured FL monthly using 2D ultrasonography (USG) for each subjects |
Countries
Indonesia
Outcome results
None listed