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The Effects of Sleep Variability in Youth

The Effects of Sleep Variability on Sleep Quality, Daytime Functioning and Cardiometabolic Regulation in Youth

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT04263428
Enrollment
41
Registered
2020-02-10
Start date
2019-06-01
Completion date
2021-01-01
Last updated
2021-05-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Sleep Variability

Brief summary

Daily sleep variability is prevalent in the young populations, yet its effects remain less clear. The experimental study aims to examine the impacts of intraindividual daily sleep variability on sleep characteristics, cardiometabolic regulations and daytime functioning in college students.

Interventions

BEHAVIORALIrregular sleep

Experimental-induced sleep variability

Sponsors

The University of Hong Kong
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
BASIC_SCIENCE
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
18 Years to 25 Years
Healthy volunteers
Yes

Inclusion criteria

* Habitual sleep duration \> 7 h/day.

Exclusion criteria

* Extreme morning- nor extreme evening-chronotype * With sleep problems * With mood and anxiety problems * With excessive daytime sleepiness * Have history of any chronic medical condition and on regular medication.

Design outcomes

Primary

MeasureTime frameDescription
Cognitive functioning - working memory7 daysworking memory as measured by 2-back task
Mood7 days (every morning and evening)mood state as measured by the Positive and Negative Affect Scale (PANAS).
Cognitive functioning - Sustained attention7 days (every morning and evening)Sustained attention as measured by psychomotor vigilance task (PVT)
Cognitive functioning - processing speed7 daysProcessing speed as measured by Digit Symbol Substitution Test (DSST)
Cognitive functioning - inhibition7 daysInhibition as measured by stop-signal reaction time (SSRT)
Subjective sleepiness7 days (every morning and evening)As measured by the Stanford Sleepiness Scalen (SSS)

Secondary

MeasureTime frameDescription
Sleep architecture7 daysSleep stagings (e.g., SWS%, REM duration) and sleep EEG spectrums as analysed from PSG recordings.
Heart rate variability7 daysResting heart rate and heart rate variability are measured in the morning, evening and during the night.
Cortisol awakening responsebaseline, post-interventionCortisol awakening response is assessed before and after the manipulation.
Sleep quality7 daysActual sleep time, sleep onset latency, wake after sleep onset and night time arousals as measured by actigraphy and PSG. Sleep satisfactory and dreams as measured by sleep diary.

Countries

Hong Kong

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026