Faecal Incontinence, Prostate Cancer
Conditions
Keywords
hypofractionated radiotherapy, quality of life, cancer survivors
Brief summary
The objective of the study is to determine the incidence of faecal incontinence in prostate cancer survivors treated with moderately hypofractionated radiation therapy and correlate the dose received by the anal sphincter with the degree of faecal incontinence.
Detailed description
The investigators know that high doses of irradiation in the anal sphincter are associated with more chronic fecal leaks in survivors irradiated by normofractionated radiotherapy prostate cancer. The safe dose of irradiation of the anal sphincter with radiotherapy modern techniques (volumetric modulated arc therapy with moderately hypofracctionation) is unknown. Urgency and faecal incontinence greatly affects the quality of life of these patients. Therefore, it is interesting to implement strategies to protect the anatomical structures involved in fecal continence. The objective of the study is to determine the incidence of faecal incontinence in prostate cancer survivors treated with modern moderately hypofractionated radiation therapy and correlate the dose received by the anal sphincter with the degree of faecal incontinence. The investigators also want to evaluate the quality of life of these patients
Interventions
RADIATIONhypofractionated radiotherapy
volumetric modulated moderately fractionated arc therapy
Sponsors
Consorci Sanitari de Terrassa
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
MALE
Age
18 Years to No maximum
Inclusion criteria
* Prostate cancer survivors treated in our department by hypofractionated radiotherapy
Exclusion criteria
* Relapse of prostate cancer * Other active cancer * Mental disorder
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| faecal incontinence after prostate radiation therapy | before radiotherapy (basal) | grade of faecal incontinence in prostate cancer patients |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Quality of life after prostate radiation therapy | 3 years after completion of radiotherapy | Quality of life in prostate cancer survivors comparing continents patients and incontinents patients |
Countries
Spain
Contacts
PRINCIPAL_INVESTIGATORJoan Lozano, MD
Consorci Sanitari de Terrassa
Outcome results
None listed