Obstructive Sleep Apnea-hypopnea Syndrome, Upper Aerodigestive Tract Neoplasms
Conditions
Keywords
Upper Aerodigestive Tract Neoplasms, Obstructive Sleep Apnea-hypopnea Syndrome, Epworth score, Ventilatory Polygraphy
Brief summary
Prospective open-label, non-randomized, monocentric, cohort study, to assess the prevalence and severity of sleep apnea syndrome in patients treated for cancer of the upper aerodigestive tract. The patient follows a usual course of care including, at the end of the treatment of his cancer of the upper aerodigestive tract, screening for obstructive sleep apnea syndrome at 3 months and 6 months (Epworth score and ventilatory polygraphy)
Detailed description
Prospective open-label, non-randomized, monocentric, cohort study, to assess the prevalence and severity of sleep apnea syndrome in patients treated for cancer of the upper aerodigestive tract. Patients are included in the study when they are hospitalized for panendoscopy. Thereafter, it takes about 1 month to start any treatment. The duration of treatment is estimated at about 5 months (the longest regimen would be induction chemotherapy followed by surgery and adjuvant complementary treatment). After which the patient follows a usual course of care including, at the end of the treatment of his cancer of the upper aerodigestive tract, screening for obstructive sleep apnea syndrome at 3 months and 6 months (Epworth score and ventilatory polygraphy).
Interventions
None listed
Sponsors
Centre Hospitalier Sud Francilien
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* macroscopic lesion suggestive of a cancerous tumour of the upper aerodigestive tract (oral cavity, oropharynx, larynx, hypopharynx, cavum, cervical lymph node metastases with an occult primary cancer) * awaiting anatomopathological confirmation
Exclusion criteria
* history of cancer of the upper aerodigestive tract * history of known obstructive sleep apnea syndrome * cancer of the thyroid, salivary glands, nose and paranasal sinuses * patients under guardianship or curatorship
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Occurence of obstructive sleep apnea syndrome | 3 months after the end of treatment for cancer of the upper aerodigestive tract | Obstructive sleep apnea syndrome is defined by an apnea-hypopnea index greater than or equal to 15 per hour |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Delay in onset of obstructive sleep apnea syndrome after completion of cancer treatment | during the 6 months follow-up | Delay in onset of obstructive sleep apnea syndrome after completion of cancer treatment |
| Epworth score | at 3 months and 6 months | The Epworth auto-questionnaire, rated from 0 (better) to 24 (worse), assess day-time sleapiness. |
| Occurence of obstructive sleep apnea syndrome | 6 months after the end of treatment for cancer of the upper aerodigestive tract | Obstructive sleep apnea syndrome is defined by an apnea-hypopnea index greater than or equal to 15 per hour |
Countries
France
Outcome results
None listed