Amblyopia
Conditions
Brief summary
Background: Amblyopia is a neurodevelopmental disorder in both monocular and binocular functions and it extends even beyond the primary visual integration centers, therefore, amblyopia is not a lazy eye but it is a lazy brain. Purpose: The investigators aimed to compare the visual outcome of occlusion therapy with virtual reality game playing as a new therapy on amblyopic children. Methods: This RCT was performed on 50 children with unilateral amblyopia ,4 to 10 years old. They were randomly divided to case and control (each= 25) groups. case group were trained binocularly using the virtual reality games through head set for one hour a day, 5 days in a week for 4 to 6 weeks. Controls occluded their non- amblyopic eyes, 2, 4 and 6 hours for mild (0.2 to 0.3 LogMAR), moderate (0.3 to 0.6 LogMAR) and severe (BCVA \< 0.6 LogMAR) amblyopia, respectively.
Interventions
DEVICEVirtual Reality
New treatment for amblyopia therapy using playing games
OTHERPatching
Patching
Sponsors
Hamideh Sabbaghi
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
TRIPLE (Subject, Caregiver, Investigator)
Eligibility
Sex/Gender
ALL
Age
4 Years to 10 Years
Healthy volunteers
Yes
Inclusion criteria
\- The best corrected visual acuity worse than 0.3 LogMAR
Exclusion criteria
* Patients with abnormal fixation * Patients with neurological problems * Patients with any types of ocular pathologies
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Best Corrected Visual Acuity (BCVA) | baseline and 6 months after training | Change from baseline BCVA at 6 months |
Contacts
Primary ContactHamideh Sabbaghi, PhD
Outcome results
None listed