Epigenetic Changes in Head and Neck Cancer

Biomarkers in Head and Neck Cancer - Epigenetic Changes and Hypermethylation of Promoter-regions

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT04260074

Enrollment

Registered

2020-02-07

Start date

2020-03-11

Completion date

2021-07-14

Last updated

2021-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Head and Neck Cancer, Head and Neck Neoplasms, Head and Neck Squamous Cell Carcinoma, Squamous Cell Carcinoma

Brief summary

With this study, the investigators will investigate the epigenetic changes, which may contribute to the development of head and neck squamous cell carcinomas.

Interventions

None listed

Study design

Observational model

CASE_CONTROL

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Yes

Inclusion criteria

Cancer group: Inclusion Criteria : * Written informed consent * Histologically confirmed oral squamous cell carcinoma

Exclusion criteria

* History of cancer * Uncontrolled comorbidity Control group: Inclusion Criteria : * Written informed consent * Normal buccal mucosal surface. * Normal ENT-examination

Design outcomes

Primary

Measure	Time frame	Description
Differences in epigenetic changes	6 months	Differences between tumor- and healthy group

Countries

Denmark

Outcome results