COPD
Conditions
Brief summary
The chronic obstructive pulmonary disease (COPD) patients with type II respiratory failure always needs PaCO2 test to monitor the changes of disease. Method used mostly nowadays to detect PaCO2 is arterial puncture which is accurate but is invasive, painful and non-dynamic. Noninvasive measurement methods includes end-tidal CO2 (PetCO2), transcutaneous CO2 (PtcCO2) which can monitor the PaCO2 dynamically and noninvasively, but their accuracy is in controversy. Common PetCO2 is especially inaccurate in COPD patients while our team find that the accuracy can be improved by prolong expiration method (PetCO2 (P)).So the investigators want to compare the accuracy of PtcCO2 and PetCO2(P) in AECOPD patients during noninvasive ventilation(NIV).
Interventions
OTHERno intervention
no intervention
Sponsors
Zhenfeng He
Study design
Observational model
OTHER
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
20 Years to 100 Years
Healthy volunteers
No
Inclusion criteria
* AECOPD patients with type II respiratory failure who need NIV treatment
Exclusion criteria
* hemodynamics is unstable; * any other lung disease despite COPD; * other diseases influencing experiments: Cognitive impairment disease mouth and nose trauma.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| partial arterial pressure of end-tidal CO2 measured by prolong expiration method [PetCO2(P)] | 2 hours | PetCO2(P) will be measured before and after NIV treatment. |
| partial arterial pressure of transcutaneous CO2 (PtcCO2) | 2 hours | PtcCO2 will be measured before and after NIV treatment. |
| partial arterial pressure of carbon dioxide (PaCO2) | 2 hours | PaCO2 will be measured before and after NIV treatment. |
Countries
China
Contacts
Primary ContactShanshan Zha, master
Outcome results
None listed