Lymphedema
Conditions
Brief summary
Researchers are trying to validate the use of ultrasound sub-hertz analysis of viscoelastisty (SAVE) method to monitor tissue-fluid dynamics and stage disease severity in patients diagnosed with lymphedema.
Interventions
DIAGNOSTIC_TESTUltrasound Procedure
Ultrasound technique that uses a compression device integrated with ultrasound imaging to perform in vivo ramp-and-hold uniaxial creep-like test on upper extremity lymphedema (UEL) in vivo.
Sponsors
Mayo Clinic
Study design
Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
OTHER
Masking
NONE
Intervention model description
The unaffected arm will be used to serve as control for the affected extremity.
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Adult (18+ years of age) * Ability to provide written consent * Has been diagnosed with Lymphedema
Exclusion criteria
* Under the age of 18 years old * Inability to provide written consent * Previous lymphovenous bypass or lymph node transfer surgery
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Viscoelasticity parameters with lymphedema as obtained using the SAVE method | Baseline | Defined as the difference in viscoelastic parameters between the arm affected with lymphedema and the unaffected extremity (affected minus unaffected) using the sub-hertz analysis of viscoelasticity method |
Countries
United States
Contacts
PRINCIPAL_INVESTIGATORAntonio Forte, MD
Mayo Clinic
Outcome results
None listed