Venous Thromboembolism
Conditions
Keywords
Venous thromboembolism, deep venous thrombosis, neurosurgery, pulmonary embolism
Brief summary
Venous thromboembolism (VTE), comprising deep venous thrombosis (DVT), pulmonary embolism (PE), or both, is a life-threatening complication in postoperative patients. VTE has been estimated an incidence ranged from 79 per 100000 to 269 per 100000 population1. The incidence of VTE rises up to 3.0% in average among all postoperative neurosurgical patients in recent studies, but the number varies in a large range according to primary diseases. This cross-sectional study was aimed to investigate the incidence, associated risk factors, prophylaxis, treatment, and outcomes of VTE in a large clinical neurosurgery center in China.
Detailed description
Venous thromboembolism (VTE), comprising deep venous thrombosis (DVT), pulmonary embolism (PE), or both, is a life-threatening complication in postoperative patients. This cross-sectional study was aimed to investigate the incidence, associated risk factors, prophylaxis, treatment, and outcomes of VTE in a large clinical neurosurgery center in China. 9010 patients underwent neurosurgery procedure were included. Distribution of age, sex, whether received PICC during perioperative period, and some special primary diseases are significantly different between VTE and non-VTE patients. Student's test and chi-square test were performed for analyses. We investigated VTE incidence, risk factors, prophylaxes, treatment and outcomes in postoperative neurosurgical patients, and summarized the VTE susceptible population of the patients, providing a VTE patient profile for neurosurgeons to concern.
Interventions
None listed
Sponsors
Huashan Hospital
Study design
Observational model
CASE_CONTROL
Time perspective
CROSS_SECTIONAL
Eligibility
Sex/Gender
ALL
Healthy volunteers
No
Inclusion criteria
Neurosurgical Inpatients. Underwent neurosurgery procedure.
Exclusion criteria
Acute or chronic respiratory failure. Acute myocardial infarction or other serious heart diseases.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Rate of VTE occurrence | 19 months | VTE incidence in postoperative neurosurgical patients during inhospital time from Jun 1,2018 to Dec 31,2019 |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Rate of complete vessel recanalization | 19 months | Complete vessel recanalization rate in postoperative neurosurgical patients during inhospital time from Jun 1,2018 to Dec 31,2019 |
| Rate of partial vessel recanalization rate | 19 months | Partial vessel recanalization rate in postoperative neurosurgical patients during inhospital time from Jun 1,2018 to Dec 31,2019 |
| Rate of bleeding events | 19 months | Bleeding events occurred in patients during VTE treatment |
Countries
China
Outcome results
None listed