Obese
Conditions
Brief summary
The study investigates whether the addition of resolution molecules can inhibit inflammation and insulin resistance in human tissue taken from obese individuals, and whether the results of these studies correlate with patient-specific resolution phenotypes.
Interventions
None listed
Sponsors
Göteborg University
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 60 Years
Inclusion criteria
* BMI 30-40 kg/m2 * Ptos (i.e. excess skin) \> 3 cm * Patient underwent gastric bypass surgery \>2 years ago * Patient has had a stable weight ≥6 months at the time of operation * Patient does not smoke (min 6 weeks prior to surgery)
Exclusion criteria
* Patients who do not understand spoken and written Swedish * American Society of Anesthesiologists (ASA) classification ≥ 3 * Neurological, orthopedic or rheumatologic injury or illness affecting physical ability * Preoperatively known hernia requiring surgical operation * Severe mental illness
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Inflammatory status | 2025 | The inflammatory status will be studied in obese patients. |
Countries
Sweden
Contacts
Primary ContactEmma Borgeson, PhD
Backup ContactChristina Biörserud, RN, PhD
Outcome results
None listed