Osteoporosis Senile, Obesity, Visceral
Conditions
Keywords
osteoporosis, anthropometrics, body composition
Brief summary
The patients who consulted to the geriatric outpatient clinic between 2018 and 2019 were included in the study. The inclusion criterions were being at or over the age of 65 and diagnosed with osteoporosis according to WHO criteria. Exclusion criteria include vertebral fracture due to known accidental traumas, history of drug therapy in the past year (biphosphonate, estrogen replacement therapy, glucocorticoids ), history of co-morbidities as malignancy, radiotherapy or chemotherapy, renal failure, hyperthyroidism, primer hyperparathyroidism, rheumatic disease or adrenal diseases. Initially, a demographic form including age, sex, comorbidities, weight, height was filled by the participants. Body mass index (BMI, ratio of height and weight, expressed as kg/m2) calculated. Patients waist and hip circumference was measured (cm). Fat percentage and skeletal muscle mass (SMM) was calculated by using bioimpedance analysis (BIA) (Tanita TBF 300; Tanita Corp., Tokyo, Japan). Skeletal muscle index (SMI) was calculated from BIA-based skeletal muscle mass with a formula as SMM/height \[m2\] \[8\]. ABSI is measured as waist circumference (m) / (BMI(kg)2/3x Height(m)5/6) \[4\]. Osteoporosis was evaluated by using dual energy x-ray absorptiometry (DXA). According to the T-scores calculated from femur neck (FN) and lumbar spine (LS), subjects divided into 3 groups as following: a) normal: T-score is greater than -1 SD, b) osteopenia: T-score is between -1 and -2.5 SD, c) osteoporosis: T-score is lower than -2.5 SD. Physical activity levels of patients were evaluated with The Rapid Assessment of Physical Activity (RAPA) aerobic assessment \[9\]. Patients divided into 5 groups as following: 1 = sedentary, 2 = underactive, 3 = regular underactive (light activities), 4 = regular underactive, and 5 = regular active). The study protocol was approved by the ethics committee (2018/0478) and all participants gave written informed consent.
Interventions
DIAGNOSTIC_TESTBody mass index
Body mass index is calculated as a ratio of height and weight, expressed as kg/m2
DIAGNOSTIC_TESTwaist circumference
waist circumference is measured as cm
DIAGNOSTIC_TESThip circumference
hip circumference is measured as cm
DIAGNOSTIC_TESTheight
height is measured as cm
DIAGNOSTIC_TESTFat percentage
Fat percentage and skeletal muscle mass (SMM) was calculated by using bioimpedance analysis (BIA) (Tanita TBF 300; Tanita Corp., Tokyo, Japan).
DIAGNOSTIC_TESTSkeletal muscle index
Skeletal muscle index (SMI) was calculated from BIA-based skeletal muscle mass with a formula as SMM/height \[m2\].
DIAGNOSTIC_TESTA body shape index (ABSI)
ABSI is measured as waist circumference (m) / (BMI(kg)2/3x Height(m)5/6)
DIAGNOSTIC_TESTDual energy x ray absorptiometry (DXA)
Osteoporosis is diagnosed with DXA scores. According to the T-scores calculated from femur neck (FN) and lumbar spine (LS), subjects divided into 3 groups as following: a) normal: T-score is greater than -1 SD (standard deviation), b) osteopenia: T-score is between -1 and -2.5 SD, c) osteoporosis: T-score is lower than -2.5 SD.
DIAGNOSTIC_TESTThe Rapid Assessment of Physical Activity (RAPA) aerobic assessment
Physical activity levels of patients were evaluated with The Rapid Assessment of Physical Activity (RAPA) aerobic assessment. Patients divided into 5 groups as following: 1 = sedentary, 2 = underactive, 3 = regular underactive (light activities), 4 = regular underactive, and 5 = regular active).
Sponsors
Istanbul Medeniyet University
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
DIAGNOSTIC
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
65 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* being at or over the age of 65 * diagnosed with osteoporosis according to WHO criteria
Exclusion criteria
* vertebral fracture due to known accidental traumas * history of drug therapy in the past year (biphosphonate, estrogen replacement therapy, glucocorticoids ) * history of co-morbidities as malignancy, radiotherapy or chemotherapy, renal failure, hyperthyroidism, primer hyperparathyroidism, rheumatic disease or adrenal diseases
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Waist circumference | 2 years | calculated as cm |
| Hip circumference | 2 years | calculated as cm |
| Fat percentage | 2 years | Fat percentage and skeletal muscle mass (SMM) was calculated by using bioimpedance analysis (BIA) (Tanita TBF 300; Tanita Corp., Tokyo, Japan) |
| Skeletal muscle index | 2 years | Fat percentage and skeletal muscle mass (SMM) was calculated by using bioimpedance analysis (BIA) (Tanita TBF 300; Tanita Corp., Tokyo, Japan). Skeletal muscle index (SMI) was calculated from BIA-based skeletal muscle mass with a formula as SMM/height \[m2\] |
| A body shape index (ABSI) | 2 years | ABSI is measured as waist circumference (m) / (BMI(kg)2/3x Height(m)5/6) |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| The Rapid Assessment of Physical Activity (RAPA) aerobic assessment | 2 years | Physical activity levels of patients were evaluated with The Rapid Assessment of Physical Activity (RAPA) aerobic assessment. Patients divided into 5 groups as following: 1 = sedentary, 2 = underactive, 3 = regular underactive (light activities), 4 = regular underactive, and 5 = regular active). |
Countries
Turkey (Türkiye)
Outcome results
None listed