Neutrophil-lymphocyte Ratio and Platelet-lymphocyte Ratio as Predictors for Adverse Events in EVAR

Neutrophil-lymphocyte Ratio and Platelet-lymphocyte Ratio as Predictors for Adverse Events in Endovascular Aneurysm Repair for Abdominal Aorticaneurysm

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT04254211

Enrollment

230

Registered

2020-02-05

Start date

2016-03-01

Completion date

2019-11-01

Last updated

2021-04-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Inflammation in EVAR

Brief summary

This study investigated the association of chronic inflammatory markers with the clinical outcome after endovascular aneurysm repair (EVAR) for abdominal aortic aneurysm.

Detailed description

The study included 230 consecutive AAA patients, treated electively by EVAR from March 2016 to February 2019. The values of simple inflammatory markers,neutrophil-lymphocyte ratio (NLR) and platelet-lymphocyte ratio (PLR), were measured pre- and postoperatively.Adverse events included any major adverse cardiovascular events (MACE), acute kidney injury and death from any cause.

Interventions

OTHERNLR

neutrophil-lymphocyte ratio (NLR) and platelet-lymphocyte ratio (PLR)

Study design

Observational model

COHORT

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Healthy volunteers

Inclusion criteria

* AAA * Elective * EVAR

Exclusion criteria

* Emergency * Open surgery

Design outcomes

Primary

Measure	Time frame	Description
NLR major cardiovascular events (MACE)	Day 4 postopertively	NLR indicator for major cardiovascular events (MACE)
PLR major cardiovascular events (MACE)	Day 4 postopertively	PLR indicator for major cardiovascular events (MACE)
NLR acute kidney injury (AKI)	Day 4 postopertively	NLR indicator for acute kidney injury (AKI)
PLR acute kidney injury (AKI)	Day 4 postopertively	PLR indicator for acute kidney injury (AKI)
NLR death	Day 4 postopertively	NLR indicator for death
PLR death	Day 4 postopertively	PLR indicator for death

Countries

Greece

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026