Aging Problems, Cardiovascular Diseases, Cardiovascular Risk Factor, Sleep, Smell Disorder
Conditions
Brief summary
The Chinese Multi-provincial Cohort Study (CMCS)-Beijing project is a sub-study in CMCS participants from Beijing, which intended to investigate the progression and determinants of atherosclerosis and aging related health problems through repeat examinations. Exam 0 to Exam 3 have been conducted during 1992 to 2012. Exam 4 is scheduled in 2020.
Interventions
Different level of cardiovascular risk factors, such as aging, hypertension, diabetes, dyslipidemia, smoke, alcohol drink, obesity and et al, associated with genetics, environments and lifestyles
Aging related health problems
Sponsors
Study design
Eligibility
Inclusion criteria
* Participants from CMCS-Beijing * sign the informed consent
Exclusion criteria
* participanting in clinical trials
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| All fatal and nonfatal acute coronary and stroke events | From date of enrollment until the date of first documented event or date of cardiovascular death, whichever came first, assessed at least 5 years | Acute coronary heart disease events included acute myocardial infarction, sudden death, and other coronary deaths. Acute stroke events included subarachnoid hemorrhage, intracerebral hemorrhage, or cerebral infarction. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| New-onset of coronary events | From date of enrollment until the date of first documented event or date of CHD death, whichever came first, assessed at least 5 years | Acute coronary heart disease events included acute myocardial infarction, sudden death, and other coronary deaths. |
| New-onset of stroke | From date of enrollment until the date of first documented event or date of stroke death, whichever came first, assessed at least 5 years | Acute stroke events included subarachnoid hemorrhage, intracerebral hemorrhage, or cerebral infarction. |
| Olfactory Disorders | From date of enrollment until date of first documented event, assessed at least 5 years | Olfactory Disorders |
| Cognitive dysfunction | From date of enrollment until date of first documented event, assessed at least 5 years | Cognitive dysfunction |
| Valvular disease | From date of enrollment until the date of first documented event or date of valvular disease death, whichever came first, assessed at least 5 years | Valvular disease |
| Total death | From date of enrollment until date of death from all cause, assessed at least 5 years | All cause death |
Countries
China