Anesthesia, Intratracheal Intubation, Surgery
Conditions
Keywords
oral care, Anesthesia, surgery, Intratracheal Intubation
Brief summary
This single-centre, single-blind, randomised controlled study with parallel-group design was conducted in Yun Ling, Taiwan between May 2019 and August 2019. Participants were randomly allocated to an intervention (mouth care using 0.12% CHX before intubation) or control (standard care) group on a 1:1 basis. This study was approved by the institutional review board of National Taiwan University Hospital, Taiwan (IRB No.201806086RINB). Each participant completed written informed consent after explanation of this study and advised that they could withdraw anytime.
Detailed description
Participants were recruited at the operation room of a teaching hospital. Participants were included if they met the following criteria: 18-80 years of age, American Society of Anesthesiologists, ASA) class 1-3, scheduled for surgery under endotracheal tube intubation general anesthesia. Patients were excluded if they were diagnosed with upper or lower respiratory tract disease, including COPD, cold, had oral ulcer, scheduled to have a respiratory-related surgical procedure, had endotracheal tube intubated.
Interventions
OTHEROral care
oral care using 20mL of 0.12% CHX and gargling with 30 seconds.
Sponsors
National Taiwan University Hospital
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
SINGLE (Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
18 Years to 80 Years
Healthy volunteers
No
Inclusion criteria
* 18-80 years of age, American Society of Anesthesiologists, ASA) class 1-3, scheduled for surgery under endotracheal tube intubation general anesthesia.
Exclusion criteria
* Patients were excluded if they were diagnosed with upper or lower respiratory tract disease, including COPD, cold, had oral ulcer, scheduled to have a respiratory-related surgical procedure, had endotracheal tube intubated, \>1 during anesthesia processes,
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Bacterial Colonization (Gram stain) | at baseline (30 minutes before surgery started) | Bacterial Colonization |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Breathing odor assessment using questionnaire | at baseline (30 minutes before surgery started) | Breathing odor assessment |
| Breathing odor assessment using halitosis detector | at baseline (30 minutes before surgery started) | Breathing odor assessment |
Countries
Taiwan
Outcome results
None listed