Aortic Dissection, Pulmonary Embolism
Conditions
Brief summary
Acute aortic dissection is rare but potentially life-threatening disease with an incidence of 5-30 cases per million, annually. Therefore prompt diagnosis is crucial. D-dimer values have been shown to be useful in the diagnosis of acute aortic dissection. Fibrinogen levels have been shown to be low, normal or high in individuals with acute aortic dissection. This study aims to investigate whether D-dimer/fibrinogen ratio can be valuable for diagnosis of acute aortic dissection.
Interventions
DIAGNOSTIC_TESTD-dimer/fibrinogen ratio
The ratio of D-dimer (ng/ml) to fibrinogen (mg/dl)
Sponsors
Dr. Lutfi Kirdar Kartal Training and Research Hospital
Study design
Observational model
CASE_CONTROL
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Diagnosis of acute aortic dissection * Diagnosis of acute pulmonary embolism * Diagnosis of non-cardiac chest pain
Exclusion criteria
* Any etiology of chest pain other than acute aortic dissection, acute pulmonary embolism, or non-cardiac chest pain * Participants who do not give consent for enrollment
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Acute aortic dissection | 24 hours | Diagnosis of acute aortic dissection confirmed by contrast enhanced computed tomography, magnetic resonance imaging, echocardiography or aortography |
Countries
Turkey (Türkiye)
Contacts
Primary ContactAvni Uygar Seyhan, M.D.
Backup ContactAhmet Can Topcu, M.D.
Outcome results
None listed