Osteoarthritis, Knee, Physical Therapy Modalities
Conditions
Brief summary
Knee osteoarthritis (OA) is one of the most common musculoskeletal disorders in the world. The aim of this project is to evaluate the additional effect of photobiomodulation therapy on the quadriceps muscle and knee joint in a blood flow restriction exercise program for individuals with knee OA. To this end, volunteers will be selected at random, aged between 40 and 65 years with pain in one knee, at least in the last 6 months, diagnosed with unilateral knee OA based on the criteria established by the American College of Rheumatology and radiographic confirmation for grades 2 or 3 of the Kellgren-Lawrence Classification, will be randomized into the following groups: (Exercises with blood flow restriction, n = 20), (Exercises with blood flow restriction + photobiomodulation, n = 20) and Exercises with blood flow restriction + placebo photobiomodulation (n = 20). 12 consecutive weeks of treatment will be carried out, with the volunteers being evaluated before and after, using the following instruments: The Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC), sit and stand test, Timed up and Go (TUG), numerical scale pain assessment (END), pain-to-pressure threshold (LDP), skin temperature: quadriceps musculature, knee joint and maximum voluntary isometric contraction (MVIC) of the muscles: quadriceps, middle gluteus. For data analysis, normality test will be used to verify the data distribution and statistical test consistent with the appropriate comparisons within and between groups, thus, two factors are considered in the comparisons, time and group. A significance level of 5% will be adopted.
Interventions
DEVICEblood flow restriction
Occlusion training is an exercise approach whereby resistance exercise or aerobic exercise is performed whilst an occlusion cuff is applied to proximal aspect of the muscle.
DEVICEPhotobiomodulation
Photobiomodulation therapy is defined as the utilization of non-ionizing electromagnetic energy to trigger photochemical changes within cellular structures that are receptive to photons.
Placebo photobiomodulation - photobiomodulation device turned off.
Sponsors
University of Nove de Julho
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
TRIPLE (Subject, Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
FEMALE
Age
40 Years to 65 Years
Healthy volunteers
No
Inclusion criteria
* knee pain to at least six months and minimum of 4 points in pain scale * diagnosis of unilateral knee OA based on criteria established by the American College of Rheumatology and radiographic confirmation for grades 2 or 3 of the Kellgren-Lawrence Classification.
Exclusion criteria
* Score on the numerical visual analog of knee pain less than 1 or greater than 8; * knee trauma; * Cognitive impairment; * Psychological disorder; * Neurological disorder (sensory or motor); * Cancer; * Diabetes any acute adverse health condition; * Signs of hip OA; * Sings cardiopulmonary disease that could prevent exercise and use of a walking assist device. * Have undergone any form of treatment involving: physiotherapy, intra-articular corticosteroids, anti-inflammatories or chondroprotectors in the last year. * If the size of the circumference of the thigh and knee does not allow the proper positioning of the photobiomodulation mesh.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Functional pain | Change from Baseline in The Western Ontario and McMaster Universities Arthritis Index at 12 weeks | The Western Ontario and McMaster Universities Arthritis Index (WOMAC) is widely used in the evaluation Knee Osteoarthritis. |
| Stiffness | Time Frame: Change from Baseline in The Western Ontario and McMaster Universities Arthritis Index at 12 weeks | The Western Ontario and McMaster Universities Arthritis Index (WOMAC) is widely used in the evaluation Knee Osteoarthritis. |
| Physical functional | Change from Baseline in The Western Ontario and McMaster Universities Arthritis Index at 12 weeks | The Western Ontario and McMaster Universities Arthritis Index (WOMAC) is widely used in the evaluation Knee Osteoarthritis. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Muscle skin temperature | Change from Baseline in the muscle skin temperature at 12 weeks | Infrared thermography, thermal imaging. Thermography uses a type of infrared technology that detects and records temperature changes on the surface of the ski. |
| Intensity of pain | Change from Baseline in The Numerical rating pain scale at 12 weeks | The Numerical rating pain scale, a simple, easily administered scale evaluates the perceived intensity of pain, using an 11-point scale from 0, representing 'no pain', to 10, which is the 'worst possible pain'. |
| Maximum voluntary isometric contraction | Change from Baseline in the Maximum voluntary isometric contraction at 12 weeks | A portable dynamometer will be used to assess muscle contraction. |
| Functional capacity for sitting and standing | Change from Baseline in The Functional capacity for sitting and standing at 12 weeks | sitting-rising test |
| Level of pressure pain | Change from Baseline in ThePressure Pain Threshold at 12 weeks | Pressure Pain Threshold in the knee with algometer dynamometer. |
Countries
Brazil
Outcome results
None listed