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Laryngomicrosurgery Under NIDP General Anesthesia Supported by THRIVE

Laryngomicrosurgery Under Nonintubated Deep Paralysis (NIDP) General Anesthesia Supported by Transnasal Humidified Rapid-insufflation Ventilatory Exchange: A Case Series Study

Status
UNKNOWN
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT04247412
Acronym
NIDP
Enrollment
20
Registered
2020-01-30
Start date
2020-04-20
Completion date
2021-12-31
Last updated
2021-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Vocal Polyp

Keywords

Laryngomicrosurgery, Nonintubated deep paralysis, Transnasal Humidified Rapid-insufflation Ventilatory Exchange

Brief summary

Laryngomicrosurgery requires deep paralysis and general anesthesia to finish the procedure. After the procedure, patients need a long time to recover. In the present study, with the support of the transnasal humidified rapid-insufflation ventilatory exchange, laryngomicrosurgery would be finished under nonintubated deep paralysis (NIDP) general anesthesia. In this case series study, the investigators will test the safety and feasibility of such a technique.

Interventions

None listed

Sponsors

RenJi Hospital
Lead SponsorOTHER

Study design

Observational model
CASE_ONLY
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to 40 Years
Healthy volunteers
No

Inclusion criteria

* elective polypectomy of unilateral vocal cord * age between 18 to 40 * be able to communicate * estimated operation time less than 15min * ASA I-II * Agree to sign written informed consent

Exclusion criteria

* pregnancy or breastfeeding women * severe gastrointestinal reflex disease * neuromuscular disease * body mass index(BMI)\>30 * predictable difficult airway. * allergy to medicine would be used in the present study including propofol, remifentanil or sugammadex

Design outcomes

Primary

MeasureTime frameDescription
Success rate of laryngomicrosurgeryFrom the day before surgery till 2 days after surgery or before dischargecomplete the surgery within 15min,nonintubated,remove the polyp entirely,recover completely after surgery, no major adverse event

Secondary

MeasureTime frame
Total days that participants stay in hospitalThrough study completion, an average 2 days.

Countries

China

Contacts

Primary ContactDiansan su, Dr.
184872238@qq.com+86 18616514088
Backup ContactYichen Fan, M.S.
mcking95@163.com+86 13482827569

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 11, 2026