Impact of Alarm Reduction on Delirium in ICU

Status

Terminated

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT04246892

Acronym

ALADIN

Enrollment

Registered

2020-01-29

Start date

2020-02-03

Completion date

2023-02-23

Last updated

2023-08-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Delirium

Brief summary

Delirium is an acute and fluctuating disturbance of consciousness and can occur in 80% of critically ill patients. Delirium is more frequent in mecanically ventilated patients and is associated with longer hospital stay, increased cognitive impairment and mortality. On the occasion of the change of the monitors in the ICU ward, allowing a total withdrawal of alarms in patients room, this study evaluates the prevalence of delirium before and after the alarm withdrawal. During the first period the patients will be monitored as usual, and during the second period patients will be monitored without alarms ringing in patients room. Delirium will be screened with a validated, clinical tool.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Inclusion criteria

* age\>18 years, admission to ICU

Exclusion criteria

* length of stay in ICU\<24 hours, moribund patient, deafness, dementia, psychiatric pathology, delirium at admission, acute neurological pathology at admission (stroke, epilepsy, neuro-infection), hepatic encephalopathy, admission for cardiac arrest, admission for voluntary drug intoxication, pregnancy

Design outcomes

Primary

Measure	Time frame	Description
prevalence of delirium, according to a ICDSC score>3	at the end on the ICU stay, an average of 6 days	prevalence of delirium in each group

Secondary

Measure	Time frame
length of stay in ICU (days)	at the end on the ICU stay, an average of 6 days
in patients presenting a delirium, duration of delirium (days) defined by the number of days with a ICDSC score>3	at the end on the ICU stay, an average of 6 days
prevalence of sub-syndromic delirium in each group, according to a ICDSC score<4 and absence of delirium	at the end on the ICU stay, an average of 6 days
length of mecanical ventilation (days)	at the end on the ICU stay, an average of 6 days

Countries

France

Outcome results