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Neonatal Evaluation of Norepinephrine Infusion in Spinal Anesthesia for Cesarean Section

Neonatal Evaluation of Norepinephrine Infusion in Spinal Anesthesia for Cesarean Section

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT04245891
Acronym
NECS
Enrollment
265
Registered
2020-01-29
Start date
2016-05-01
Completion date
2017-11-30
Last updated
2026-06-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Caesarean Section;Stillbirth

Brief summary

This retrospective study aims to evaluate the fate of children born by cesarean section under spinal anesthesia with or without norepinephrine as vasopressor support for anesthesia. The main objective is to compare the initial Apgar score. The records of patients who received norepinephrine are compared to those without norepinephrine. To limit the biases of this type of study, the investigators will apply a propensity score that will include as a variable: age, ASA score, comorbidity, urgency. The patients analysed correspond to the period 2016-2017.

Interventions

None listed

Sponsors

Centre Hospitalier Universitaire de Nīmes
Lead SponsorOTHER

Study design

Observational model
OTHER
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
FEMALE
Age
18 Years to No maximum

Inclusion criteria

* age \> 18 * Spinal Anesthesia for Cesarean Section

Exclusion criteria

* sub epidural cesarean section * contraindication to spinal anesthesia (allergy, severe heart disease, coagulopathy)

Design outcomes

Primary

MeasureTime frameDescription
lactate levelJust after the birth of the newborn babyThe primary endpoint is the Umbilical Cord Lactate levels

Secondary

MeasureTime frameDescription
APGAR Score1, 5 and 10 minutes after birthAPGAR Score
Umbilical Cord arterial PHJust after the birthUmbilical Cord arterial PH
Umbilical Cord venous PHJust after the birthUmbilical Cord venous PH
maternal arterial tension during cesarean section0, 5,10,15, 20 25, 30,35,40 minutes after spinal anesthesiamaternal arterial tension during cesarean section
incidences of mother nausea and vomitingfrom beginning to cesarean section endincidences of mother nausea and vomiting
use of vasopressorsfrom beginning to cesarean section enduse of vasopressors

Countries

France

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Jun 19, 2026