Clinical Outcomes of Bio-MA and ProRoot MTA in Endodontic Treatment

Clinical Outcomes of Bio-MA and ProRoot MTA in Non-surgical and Surgical Endodontic Treatment: a Randomized Controlled Clinical Trial

Status

UNKNOWN

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT04243993

Enrollment

Registered

2020-01-28

Start date

2017-07-01

Completion date

2024-12-31

Last updated

2020-01-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Clinical Outcome, Endodontic Disease

Brief summary

The purpose of this study is to compare the endodontic outcomes of Bio-MA and ProRoot MTA in pulpotomy, orthograde MTA apical barrier, root perforation repair, endodontic microsurgery.

Detailed description

The patients were recruited at the Endodontic clinic, Faculty of Dentistry, Mahidol University, Thailand. Each treatment was provided following the standard protocol. The calcium silicate based material (Bio-MA or ProRoot MTA) was randomly selected and used in the treatment. The patients were periodically recalled at 6 to 12 months. The outcome of the three treatments based on the clinical and radiographic criteria was assessed by the calibrated examiners and interpreted as ''healed/healing or ''disease.''

Interventions

OTHERCalcium silicate cement

Calcium silicate cement for using in endodontic treatments i.e. pulpotomy, orthograde MTA apical barrier, root perforation repair, and endodontic microsurgery.

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

DOUBLE (Subject, Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

10 Years to 65 Years

Healthy volunteers

Yes

Inclusion criteria

* Teeth treated with pulpotomy, orthograde MTA apical barrier, root perforation repair or endodontic microsurgery

Exclusion criteria

* Teeth with un-restorable condition * Teeth with crack or fracture * Teeth with external or internal root resorption * Teeth with chronic periodontitis with marginal bone loss more than 5 mm

Design outcomes

Primary

Measure	Time frame	Description
Healed rate	At least 1 year recall	No clinical sign and symptoms and periapical area in radiograph is normal. Describe in percentage.
Healing rate	At least 1 year recall	No clinical sign and symptoms and periapical lesion in radiograph is reduce in size. Describe in percentage.
Disease rate	At least 1 year recall	Clinical sign and symptoms is present and/or periapical lesion in radiograph is unchange or enlarge. Describe in percentage.

Countries

Thailand

Contacts

Primary ContactDanuchit Banomyong, Ph.D.

danuchit.ban@mahidol.ac.th022007622

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026