Interrupting Prolonged Sitting With Periodic Interval Exercise: Effect on Postprandial Lipemia

Status

UNKNOWN

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT04241081

Enrollment

Registered

2020-01-27

Start date

2020-01-31

Completion date

2020-05-31

Last updated

2020-01-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hypertriglyceridemia, Sedentary Behavior

Brief summary

Investigating the effects of interrupting various lengths of prolonged sitting with bike sprints on post prandial lipemia the next day. We will conduct three trials, one control, one with two-hour sitting intervals (total of 4 bouts of bike sprints) and one with 6-hour sitting intervals I total of two bouts of bike sprints). A milkshake high fat tolerance test will be conducted the next day and whole body fat oxidation as well as triglyceride area under the curve will be measured every hour for the duration of the 6-hour test.

Interventions

BEHAVIORALInterrupting Prolonged Sitting with Periodic Interval Exercise: Effect on Postprandial Lipemia

This is a behavioral intervention designed to determine the effect of breaking up prolonged bouts of sitting every 2 hours and every 6 hours with 5 sets of 4 second bouts of maximum effort bicycle ergometer accelerations compared to sitting alone on the blood triglyceride response and whole body fat oxidation after a high fat meal.

Study design

Allocation

RANDOMIZED

Intervention model

CROSSOVER

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to 65 Years

Healthy volunteers

Yes

Inclusion criteria

* Inactive or recreational healthy adults aged 18-65 years old.

Exclusion criteria

* Lactose intolerance, cardiovascular or metabolic diagnoses, medications for cardiovascular or metabolic diagnoses, orthopedic issues barring cycling.

Design outcomes

Primary

Measure	Time frame	Description
Triglyceride area under the curve	6 hour long high fat tolerance test	Blood measurements baseline and every hour during a high fat tolerance test.

Secondary

Measure	Time frame	Description
Whole body fat oxidation	10 min, baseline, 2 hours post ingestion of shake, 4 hours, 6 hours.	Expired gas collection and measurement of expired gas concentrations in mass spectrometer, baseline and every two hours during high fat tolerance test.

Countries

United States

Contacts

Primary ContactRebecca braden, BS

rebecca.braden@utexas.edu4422156656

Backup ContactEdward Coyle, PhD

coyle@austin.utexas.edu512 471 8596

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026