Breast Cancer
Conditions
Brief summary
local and regional anesthesia have been introduced with the goal of reducing the side effects associated with general anesthesia and IV opioid analgesia.our hypothesis is that ultrasound-guided interscalene brachial plexus block and erector spinae plane block will provide efficient surgical anesthesia and postoperative analgesia after modified radical mastectomy.
Detailed description
inadequate analgesia after modified radical mastectomy with axillary lymph node dissection may occur with most of regional anesthesia. pain in the axilla and upper limb is related to ineffective block of medial and lateral pectoral nerves as long thoracic and thoracodorsal nerves, leading to inadequate analgesia.The aim of this study is to evaluate the efficacy and safety of ultrasound-guided interscalene brachial plexus block and erector spinae plane block for providing surgical anesthesia and postoperative analgesia after modified radical mastectomy.
Interventions
OTHERregional anesthesia
combination of erector spinae plane block and interscalene block for anesthesia in modified radical mastectomy surgeries with axillary lymph node dissection
Sponsors
Dr. Mohamed Elsayed Afandy
Tanta University
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
FEMALE
Age
40 Years to 85 Years
Healthy volunteers
No
Inclusion criteria
* Female patients aged 40-85 years old * American Society of Anesthesiologists' physical status III and IV * Planned for modified radical mastectomy with axillary lymph node dissection
Exclusion criteria
* Patient refusal * Neurological or psychiatric disorders * Local infection at injection site * Spine or chest wall deformity * Allergy or any contraindication to any of the study drugs * Opioid or alcoholic addiction * Chronic pain of any cause * Uncooperative patients.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Success rate of the regional blocks | from the start to the end of the operation | completion of the surgery without need of general anesthesia. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| duration of the blocks | 24- hours in the postoperative period | Time to first request of rescue analgesia postoperative |
| Patients' satisfaction | 24-hours postoperative | degree of patients' satisfaction |
| Any adverse events | 24-hours postoperative | postoperative nausea and vomiting, local anesthetic toxicity, desaturation, bradypnea,hypotension, bradycardia or somnolence |
Countries
Egypt
Outcome results
None listed