Coronary Artery Disease, Percutaneous Coronary Intervention, Periprocedural Myocardial Injury
Conditions
Brief summary
This is a single-center, observational, prospective study. This study aims to observe the effect of periprocedural myocardial injury on cardiovascular events in patients undergoing elective percutaneous coronary intervention, and to detect the levels of serum inflammatory factors before and after intervention to predict the occurrence of periprocedural myocardial injury and its association with cardiovascular events.
Interventions
None listed
Sponsors
Shanghai Zhongshan Hospital
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 85 Years
Healthy volunteers
No
Inclusion criteria
* underwent elective coronary stenting * patients permit informed consents
Exclusion criteria
* acute STEMI * NYHA class III-IV heart failure * moderate-to-severe valvular disease * missing post-PCI troponin results * active infection, respiratory failure * liver dysfunction (liver enzyme \>3xURL or bilirubin \>2xURL), * malignancy and systemic connective tissue disease * unable to get a informed consents
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Major cardiac events | 12 months after PCI | cardiac death, target vessel revascularization, target lesion revascularization, non-fatal myocardial infarction, heart failure, angina pectoris |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Serum level of inflammatory factors | 1 day after PCI | Serum level of inflammatory factors including TNFα, IL-6 and so on. |
Countries
China
Contacts
Primary ContactZhangwei Chen, MD
Backup ContactDanbo Lu, PhD
Outcome results
None listed