Distal Radial Artery Approach to Prevent Radial Artery Occlusion (DAPRAO)

Distal Radial Artery Approach to Prevent Radial Artery Occlusion

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT04238026

Acronym

DAPRAO

Enrollment

282

Registered

2020-01-23

Start date

2019-05-02

Completion date

2020-03-31

Last updated

2020-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Radial Artery Occlusion

Brief summary

The main complication of transradial intervention is radial artery occlusion (RAO). This is relevant because it limits the radial approach for future interventions and disables this conduit for coronary bypass grafts and arteriovenous fistula. Observational studies suggest that distal radial access could reduce RAO incidence. The primary endpoint of our study is to compare the efficacy of the distal and proximal transradial approaches in terms of RAO incidence. The safety endpoint is the incidence of complications between these two methods.

Interventions

PROCEDUREDistal radial artery approach

Use of distal radial artery approach in coronary angiography and angioplasty

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

PREVENTION

Masking

NONE

Intervention model description

Two randomized groups, one receiving traditional radial access and the other receiven distal radial access

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Perceptible radial artery pulse * Diagnostic or interventional procedure feasible to be performed with radial access.

Exclusion criteria

* Myocardial infarction with ST segment elevation in time for primary angioplasty. * Cardiogenic shock or hemodynamic instability. * Clinical, plethysmography or ultrasound suggestive of occlusion of the radial artery * Prior recent radial artery access (1 month)

Design outcomes

Primary

Measure	Time frame	Description
The primary endpoint of our study is to compare the efficacy of the distal and proximal transradial approaches in terms of RAO incidence.	The RAO will be evaluated 24 hours after the procedure by ultrasound examination and was defined as the absence of both color pattern and pulsed wave registry.	The primary endpoint of our study is to compare the efficacy of the distal and proximal transradial approaches in terms of RAO incidence.

Countries

Mexico

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026