Clinic Features and Outcome of BPD (SGBPD)

Clinic Features and Long-term Outcome of Different Subgroups of Brochopulmonary Dysplasia in Preterm Infants

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT04237844

Enrollment

300

Registered

2020-01-23

Start date

2020-12-01

Completion date

2021-12-30

Last updated

2021-11-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Bronchopulmonary Dysplasia

Brief summary

This study described the perinatal high-risk factors and clinical manifestations of the children, and compared the high-risk factors, clinical manifestations and prognosis of BPD among different clinical subtypes by comparison between groups. BPD grading was performed using the 2018 grading standard to compare the distribution of I/II/III BPD among different groups.

Interventions

None listed

Study design

Observational model

CASE_CONTROL

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Healthy volunteers

Inclusion criteria

1. Premature infants born at \<32 weeks of gestational age; 2. hospitalization time ≥ 14 days; 3. The clinical medical records are complete

Exclusion criteria

* • 1) Children with congenital heart, lung malformation and definite chromosomal diseases; 2) children gave up treatment halfway; 3) corrected gestational age 36 weeks before death, the cause of death was confirmed as factors other than respiratory system.

Design outcomes

Primary

Measure	Time frame	Description
Days of Mechanical Ventilation	up to 12 months after birth	days during which the infants were given mechanical ventilation
Serious respiratory mobidities	up to 18 months after birth	occurence of at least one of the following: tracheostomy, continued hospitalization for respiratory reasons at or beyond 50weeks PMA; continued oxygen supplement or respiratory support beyond 12months after birth; readmission for respiratory reasons.
Duration of first hospital stay	up to 12 months after birth	days between admission and first discharge
Days with oxygen supplement	up to 12 months after birth	days during which the infants were given oxygen
Mortality	up to 12 months after birth	Different subtype of BPD infants against the total BPD infants in corresponding group

Secondary

Measure	Time frame	Description
length	up to 18months after birth	the measure of infant's weight
head circumference	up to 18months after birth	the measure of infant's head circumference, which is the occipital-frontal circumference
weight	up to 18months after birth	the measure of infant's length

Countries

China

Outcome results