Behavioral Dynamics, Visual Impairment
Conditions
Brief summary
An individual senses the world and reflects feedbacks via independent behaviors. Such precise collaboration of the sensory and behavioral systems is fundamental to survival and evolution. When a sensory modality is altered, the behavioral system has the potential to fit in a substitute modality. However, the specific dynamics of human behaviors in response to sensory loss remain largely unknown due to the paucities of representative situations and large-scale samples. Here, the investigators focused on thousands of human infants who suffered varying degrees of visual stimuli deficiency in early stages, while their behavioral systems remained sensitive and thus retained high behavioral plasticity. Having access to this unique population provides an unprecedented opportunity to investigate the effect of diverse visual conditions on the behavioral system and develop a domestic apparatus for screening visual impariment of infants.
Interventions
BEHAVIORALVideo recording for behaviors
A domenstic apparatus, scenario, and procedure is applied to record all the behavioral phenotypes. For each standardized procedure, the guardian sits in the chair, holding the infant facing the mobile phone screen. Each infant is given a few minutes to adapt to the surroundings and to be calm before recording. No hints or simulations are permitted during the entire process. The recording process lasted for about 3 minutes to ensure that behavioral phenotypes could be completely recorded.
Sponsors
Sun Yat-sen University
Study design
Observational model
CASE_CONTROL
Time perspective
CROSS_SECTIONAL
Eligibility
Sex/Gender
ALL
Age
No minimum to 4 Years
Healthy volunteers
Yes
Inclusion criteria
* Younger than 4 years of age
Exclusion criteria
* Any brain and mental illnesses, or other known illnesses that may affect the behavioral patterns
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| The AUC of model based on analyzing the behavioral dynamics | baseline | Normal or abnormal behavioral dynamics of infants are recorded by mobile phones. Five experienced ophthalmologists identify the occurence of abnormal behaviors independently, and 2 professors with over 10 years of experience in pediatric ophthalmology department are consulted in cases of disagreement. The AUC of model based on analyzing the behavioral dynamics will be calculated. |
Countries
China
Outcome results
None listed