Schizophrenia
Conditions
Keywords
Sorce-monitoring
Brief summary
Source-monitoring is a cognitive process that refers to the ability to remember the source of an information. Source-monitoring processes are usually studied using experimental behavioral tasks. These tasks, which are very heterogeneous, are not all available in French and, for the most part, cannot be used in neuroimaging protocols. The aim of this project is to develop an experimental task which allows the measurement of source-monitoring performances, and which is adapted to neuroimaging protocols in a French-speaking population.
Detailed description
The study will include 2 steps: 1) validation of the verbal material necessary for the creation of the source-monitoring task and 2) testing the task.
Interventions
OTHERQuestionnaire
Subjects will complete a verbal material scoring questionnaire
OTHERCognitive tests
Subjects will complete two source-monitoring tasks: the source-monitoring task which will be created from step 1 as well as the task of reference
Sponsors
Hôpital le Vinatier
Study design
Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
OTHER
Masking
NONE
Intervention model description
For step 1, two populations of participants: 30 healthy volunteers and 30 patients with schizophrenia will have to complete a verbal material scoring questionnaire. For step 2, two populations of participants: 30 healthy volunteers and 30 patients with schizophrenia will have to complete the source-monitoring task which will be created from step 1 as well as the task of reference (Brunelin et al., 2008).
Eligibility
Sex/Gender
ALL
Age
18 Years to 45 Years
Healthy volunteers
Yes
Inclusion criteria
* Men and Women aged between 18 and 45 * Having given their written informed consent * Native French speakers * Normal or corrected-to-normal vision * Education level greater than or equal to 8 (in years) * For the healthy control group, no history of previous diagnosed psychiatric disorders (according to the criteria of the Diagnostic and Statistical Manual of Mental Disorders - DSM5), absence of first-degree relatives diagnosed with spectrum disorder schizophrenia and bipolar disorder (DSM). * For the schizophrenia patients group, meeting the DSM5 criteria for schizophrenia.
Exclusion criteria
* Do not consent to be included in the study * History of hearing impairments * People who cannot read * Presence of neurological or somatic diseases * Being under tutorship or curatorship
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Source-monitoring performances | one day | Performances (calculated as the number of accurate source responses and the number of errors) obtained at the new source-monitoring task and at the source-monitoring task of reference (Brunelin et al., 2006). |
Countries
France
Contacts
Primary ContactLydie Sartelet
Outcome results
None listed