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Eye Movement and Cognitive Dysfunction

The Development of an Artificial Intelligence Platform for Screening and Referral of Cognitive Dysfunction

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT04236375
Acronym
EMCD
Enrollment
1539
Registered
2020-01-22
Start date
2020-09-01
Completion date
2025-07-30
Last updated
2026-04-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cognitive Dysfunction, Eye Movement Disorder

Brief summary

There is association between eye movement disorder and cognitive dysfunction. Therefore, utilizing eye movement and screening for cognitive dysfunction is feasible. In the present study, the investigators will develop an artificial intelligence platform to screening for cognitive dysfunction by inspecting the function of eye movement. Futher more, based on the screening results, the platform will offer referral suggestions.

Interventions

None listed

Sponsors

Sun Yat-sen University
Lead SponsorOTHER

Study design

Observational model
CASE_CROSSOVER
Time perspective
CROSS_SECTIONAL

Eligibility

Sex/Gender
ALL
Age
45 Years to No maximum
Healthy volunteers
Yes

Inclusion criteria

* ①Subjects who are diagnosed as mild cognitive decline, Alzheimer's disease, Vascular dementia, Lewy body dementia, Frontotemporal dementia, other dementia and normal by neurologist. * ②Subjects who can cooperate with the inspection. * ③Subjects who agree to participate in the study and sign the consent form

Exclusion criteria

* ①Subjects who cannot do the inspection. * ②Subjects who suffer from diseases that compromise the inspection.

Design outcomes

Primary

MeasureTime frameDescription
Area under the curveup to 1 monthAUC values for predicting whether subject has cognitive impairment or not

Secondary

MeasureTime frameDescription
Accuracy, true positive rate, and true negetive rateup to 1 monthThe performance of this artificial platform

Countries

China

Contacts

STUDY_CHAIRHaotian Lin, M.D.,Ph.D

Zhongshan Ophthalmic Center, Sun Yat-sen University

STUDY_DIRECTORXun Wang, M.D.,Ph.D

Zhongshan Ophthalmic Center, Sun Yat-sen University

PRINCIPAL_INVESTIGATORShuyi Zhang, M.D.

Zhongshan Ophthalmic Center, Sun Yat-sen University

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Apr 14, 2026