Pain, Postoperative
Conditions
Keywords
hyperalgesia, brachial plexus block, remifentanil
Brief summary
The investigators will evaluate the influence of intraoperative remifentanil infusion on the postoperative hyperalgesia in patients receiving rotator cuff repair after brachial plexus block for postoperative analgesia.
Detailed description
The study will include 68 patients undergoing rotator cuff repair. All patients will receive brachial plexus block for postoperative analgesia, followed by general anesthesia. In the experimental group, remifentanil infusion will not be used intraoperatively, and in the control group, remifentanil will be infused. After surgery, both groups will be given the same postoperative pain management using patient controlled analgesia(PCA), and pain patterns will be assessed using the Numerical rating scale (NRS) at 4 hour intervals for 24 hours. The primary end point of this study is the total dose of PCA medication over 24 hours.
Interventions
DRUGNot used remifentanil infusion
Remifentanil is not used during operation
Sponsors
Seoul National University Hospital
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
DOUBLE (Subject, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
20 Years to 70 Years
Healthy volunteers
Yes
Inclusion criteria
* ASA class I,II,III * Patients undergoing arthroscopic rotator cuff repair surgery under general anesthesia after interscalen brachial plexus block for post operative analgesia * Age ranges from 20 to 70
Exclusion criteria
* Patients who didn't agree to study * Patients can't control PCA(Patient-Controlled-Analgesia) independently * Patients who have conciousness disorder or can't express their pain level by NRS(Numeric Rating Scale) system * Patients who have severe respiratory disease or hepatic failure * Patinets who have known neuropathy or coagulopathy * Pregnancy * Patients with allegies to the drugs used in this study
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Total infused dose of patient controlled analgesia(PCA) drug during 24 hours | From end of operation to the 24hours after operation | Total infused dose of patient controlled analgesia(PCA) drug during first 24 hours after rotor cuff repair under general anesthesia |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Numerical Ratings Scale | Pain levels are checked using Numerical Ratings Scale at 4 hour intervals for 24 hours after surgery | Degree of pain is assessed using Numerical Ratings Scale at 4 hours for 24 hours after operation. The patients choose one of the digits from 0 to 10, the zero-point is painless, and the ten-point means the one with the most severe pain. |
| Total patient's trial to PCA bolus infusion | 24 hours after surgery | The total number of times patients press the infusion button on the PCA to control pain |
| Incidence of postoperative nausea and vomiting | 24 hours after surgery | Postoperative nausea and vomiting is assessed at 24hr after surgery by a face-to face interview |
Countries
South Korea
Outcome results
None listed