Prescribing Exercise to Cancer Patients At High-Risk for Falls

Status

Completed

Phases

Phase 1

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT04236154

Enrollment

Registered

2020-01-22

Start date

2020-09-03

Completion date

2024-08-26

Last updated

2024-10-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cancer

Keywords

Exercise, Falls

Brief summary

Falls are common and catastrophic in cancer patients. Cancer patients are vulnerable to falls due to muscle loss. In prescribing exercise in a data driven manner to cancer patients, our hypothesis is this prescription for exercise will eventually be demonstrated to reduce the occurrence of injurious falls.

Interventions

OTHERPedometer

Participants will wear a pedometer for 4 days at baseline, and 4-6 weeks later. Baseline readings will be used to derive an individualized exercise program for each participant based on the assigned experimental arm.

OTHERActigraph

Participants will wear a Actigraph for 4 days at baseline and 4-6 weeks later. Baseline readings will be used to derive an individualized exercise program for each participant based on the assigned experimental arm.

OTHERPerturbation Treadmill

Participants will walk on an instrumented treadmill while wearing a safety harness at baseline and 4-6 weeks later. The perturbation treadmill will assess an individual's risk for falling. Baseline readings will be used to derive an individualized exercise program for each participant based on the assigned experimental arm.

Study design

Allocation

Intervention model

SINGLE_GROUP

Primary purpose

SUPPORTIVE_CARE

Masking

NONE

Intervention model description

The investigator will incrementally increase the exercise prescription for groups of patients.

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Any cancer diagnosis, as documented in medical record, other than non-melanoma skin cancer. * No issues such as unstable angina or loss of a limb that would preclude exercise.

Exclusion criteria

* Diagnosis of non-melanoma skin cancer * Unstable angina * Loss of limb, which limits exercise capabilities at the discretion of the Principal Investigators * Pregnant women

Design outcomes

Primary

Measure	Time frame	Description
ABC Activities Specific Balance Confidence Scale (exploratory outcome)	Change from baseline ABC scale at 4-6 weeks	Patient Reported Outcome 0% No confidence, 100% Complete Confidence, higher score= better outcome

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026