RSA Study on the Behaviour of the Growth Plate During and After Temporary Hemi-epiphysiodesis and Epiphysiodesis

Behaviour of the Growth Plate in Patients Operated With Either Permanent or Temporary Hemi-epiphysiodesis or Epiphysiodesis Through by the Use of Radiostereometric Analysis (RSA)

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT04235517

Enrollment

Registered

2020-01-22

Start date

2017-01-31

Completion date

2027-01-31

Last updated

2025-09-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anisomelia, Deformity of Limb

Keywords

LLD, guided growth

Brief summary

By using radiostereometric analysis (RSA) we will be able to study growth during and after temporary epiphysiodesis and with great accuracy be able to detect asymmetric growth following this procedure. By using the same method we also want to analyse patients with axial deviations operated with guided growth (tension band plating) to study the growth during and after the procedure and be able to set the correct timing for removal of the implant.

Detailed description

The RSA method consists of implantation of small tantalum beads on either side of the physis during surgery on the the physis. Later analysis of the RSA Pictures with the RSA-method will give us an microscopically accurate measure of the growth in three planes.

Interventions

OTHERTemporary hemi-epiphysiodesis or epiphysiodesis

Tension band plate (eight-plate, pedi plate), staple or locking plate

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

3 Years to 16 Years

Inclusion criteria

* Children with idiopathic axial deviations in the lower extremities * Children with limb length discrepancys where timing of epiphysiodesis is difficult because of a big discrepancy in skeletal age and chronological age

Exclusion criteria

* Children with axial deviations and pathological physis

Design outcomes

Primary

Measure	Time frame	Description
Behaviour of the growth plate during and after temporary hemi-epiphysiodesis and epiphysiodesis	4 years	Radiostereometric analysis of growth

Countries

Norway

Contacts

Primary ContactAnne B Breen, MD

anneb3@ous-hf.no92226905

Backup ContactJoachim Horn, MD,PHD

jhorn@ous-hf.no48047706

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026